Recombinant Human NFATC2, His-tagged
Cat.No. : | NFATC2-29251TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 320-849 (530 amino acids) of Human NFAT1 with an N terminal His tag. Predicted mwt: 60 kDa; |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Conjugation : | HIS |
Source : | E. coli |
Tissue specificity : | Expressed in thymus, spleen, heart, testis, brain, placenta, muscle and pancreas. |
Form : | Lyophilised:Reconstitute with 85 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | GLPRHIYPAVEFLGPCEQGERRNSA PESILLVPPTWPKPL VPAIPICSIPVTASLPPLEWPLSSQ SGSYELRIEVQPK PHHRAHYETEGSRGAVKAPTGGHPV VQLHGYMENKPLG LQIFIGTADERILKPHAFYQVHRIT GKTVTTTSYEKIVGN TKVLEIPLEPKNNMRATIDCAGILK LRNADIELRKGET DIGRKNTRVRLVFRVHIPESSGRIV SLQTASNPIECSQ RSAHELPMVERQDTDSCLVYGGQQM ILTGQNFTSESKVVFTEKTTDGQQI WEMEATVDKDKSQPNMLFVEIPEYR NKH IRTPVKVNFYVINGKRKRSQPQHFT YHPVPAIKTEPTD EYDPTLICSPTHGGLGSQPYYPQHP MVAESPSCLVATM APCQQFRTGLSSPDARYQQQNPAAV LYQRSKSLSPSLLGY QQPALMAAPLSLADAHRSVLVHAGS QGQSSALLHPSPT NQQASPVIHYSPTNQQLRCGSHQEF QHIMYCENFAPGT TRPGPPPVSQGQRLSPGSYPTVIQQ QNA |
Sequence Similarities : | Contains 1 RHD (Rel-like) domain. |
Gene Name : | NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 [ Homo sapiens ] |
Official Symbol : | NFATC2 |
Synonyms : | NFATC2; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2; nuclear factor of activated T-cells, cytoplasmic 2; NF ATP; NFAT1; NFATp; |
Gene ID : | 4773 |
mRNA Refseq : | NM_001136021 |
Protein Refseq : | NP_001129493 |
MIM : | 600490 |
Uniprot ID : | Q13469 |
Chromosome Location : | 20q13.2 |
Pathway : | Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; |
Function : | DNA binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; |
Products Types
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NFATC2-181H | Recombinant Human NFATC2 protein, MYC/DDK-tagged | +Inquiry |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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