"PDCD4" Related Products

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Recombinant Human PDCD4

Cat.No. : PDCD4-30797TH
Product Overview : Recombinant full length Human PDCD4 with proprietary tag; 77.7 kDa inclusive of tag. AAH31049
Description : This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.
Protein length : 470 amino acids
Molecular Weight : 77.700kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Up-regulated in proliferative cells. Highly expressed in epithelial cells of the mammary gland. Reduced expression in lung cancer and colon carcinoma.
Biological activity : This product is useful for Antibody Production and Protein Array
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Glutathione is reduced.
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the PDCD4 family.Contains 2 MI domains.
Gene Name : PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) [ Homo sapiens ]
Official Symbol : PDCD4
Synonyms : PDCD4; programmed cell death 4 (neoplastic transformation inhibitor); programmed cell death protein 4; H731; nuclear antigen H731;
Gene ID : 27250
mRNA Refseq : NM_001199492
Protein Refseq : NP_001186421
MIM : 608610
Uniprot ID : Q53EL6
Chromosome Location : 10q24
Pathway : mTOR signaling pathway, organism-specific biosystem;
Function : RNA binding; binding; protein binding;

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