Recombinant Human RAD18
Cat.No. : | RAD18-29578TH |
Product Overview : | Recombinant full length Human RAD18 (aa 1-495) with a proprietary tag; 83.2 kDa inclusive of tag. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif.Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. |
Protein length : | 495 amino acids |
Molecular Weight : | 83.200kDa inclusive of tags |
Source : | Wheat germ |
Biological activity : | useful for Antibody Production and Protein Array |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: (Glutathione is reduced) |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the RAD18 family.Contains 1 RING-type zinc finger.Contains 1 SAP domain.Contains 1 UBZ-type zinc finger. |
Gene Name : | RAD18 RAD18 homolog (S. cerevisiae) [ Homo sapiens ] |
Official Symbol : | RAD18 |
Synonyms : | RAD18; RAD18 homolog (S. cerevisiae); E3 ubiquitin-protein ligase RAD18; RNF73; |
Gene ID : | 56852 |
mRNA Refseq : | NM_020165 |
Protein Refseq : | NP_064550 |
MIM : | 605256 |
Uniprot ID : | Q9NS91 |
Chromosome Location : | 3p25-p24 |
Function : | Y-form DNA binding; damaged DNA binding; ligase activity; metal ion binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
RAD18-1151H | Recombinant Human RAD18 Protein (1-495 aa), His-SUMO-tagged | +Inquiry |
RAD18-1848H | Recombinant Human RAD18 Protein, His (Fc)-Avi-tagged | +Inquiry |
Rad18-5347M | Recombinant Mouse Rad18 Protein, Myc/DDK-tagged | +Inquiry |
RAD18-29579TH | Recombinant Human RAD18 | +Inquiry |
RAD18-2315C | Recombinant Chicken RAD18 | +Inquiry |
◆ Lysates | ||
RAD18-2561HCL | Recombinant Human RAD18 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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