Recombinant Human S100A12, His-tagged
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| Cat.No. : | S100A12-30229TH |
| Product Overview : | Recombinant full length Human S100A12 with an N terminal His tag; 101 amino acids with tag, predicted MWt: 11.6 kDa. |
| Description : | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21.This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. |
| Protein length : | 91 amino acids |
| Conjugation : | HIS |
| Molecular Weight : | 11.600kDa inclusive of tags |
| Source : | E. coli |
| Tissue specificity : | Monocytes and lymphocytes. |
| Form : | Lyophilised:Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Filter the product by an appropriate sterile filter before using it in the cell culture. |
| Purity : | by SDS-PAGE |
| Storage buffer : | Preservative: NoneConstituents: 50mM Sodium chloride, 20mM Tris, pH 7.5 |
| Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
| Sequences of amino acids : | MKHHHHHHAS TKLEEHLEGI VNIFHQYSVR KGHFDTLSKG ELKQLLTKEL ANTIKNIKDK AVIDEIFQGL DANQDEQVDFQEFISLVAIA LKAAHYHTHK E |
| Sequence Similarities : | Belongs to the S-101 family.Contains 2 EF-hand domains. |
| Gene Name : | S100A12 S100 calcium binding protein A12 [ Homo sapiens ] |
| Official Symbol : | S100A12 |
| Synonyms : | S100A12; S100 calcium binding protein A12; S100 calcium binding protein A12 (calgranulin C) , S100 calcium binding protein A12 (calgranulin C); protein S100-A12; CAAF1; CAGC; CGRP; ENRAGE; MRP6; p6; |
| Gene ID : | 6283 |
| mRNA Refseq : | NM_005621 |
| Protein Refseq : | NP_005612 |
| MIM : | 603112 |
| Uniprot ID : | P80511 |
| Chromosome Location : | 1q21 |
| Pathway : | Activated TLR4 signalling, organism-specific biosystem; Advanced glycosylation endproduct receptor signaling, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88 cascade initiated on plasma membrane, organism-specific biosystem; |
| Function : | RAGE receptor binding; RAGE receptor binding; calcium ion binding; protein binding; zinc ion binding; |
◆ Recombinant Protein
| S100A12-33H | Recombinant Human S100A12 protein, Myc/DDK-tagged | +Inquiry |
| S100A12-2002H | Recombinant Human S100A12 Protein, His-tagged | +Inquiry |
| S100A12-063H | Recombinant Human S100A12 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
| S100A12-2483H | Recombinant Human S100A12, GST-tagged | +Inquiry |
| S100A12-204H | Recombinant Human S100A12, Fc-tagged, C13&N15 Labeled | +Inquiry |
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◆ Lysates
| S100A12-2094HCL | Recombinant Human S100A12 293 Cell Lysate | +Inquiry |
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S100A1S100A10S100A11S100A12S100A13S100A14S100A16S100A2S100A3S100A4S100A5S100A6S100A7S100A8S100A9S100BS100GS100PS100ZS100A7AS1PR1S1PR3S1PR4S100PBPS1PR5S. aureusS1PR2S100A7L2S100vpSS6K Substrate
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