"S100A12" Related Products


Recombinant Human S100A12, His-tagged

Cat.No.: S100A12-30229TH
Product Overview: Recombinant full length Human S100A12 with an N terminal His tag; 101 amino acids with tag, predicted MWt: 11.6 kDa.
Description: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21.This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities.
Protein length: 91 amino acids
Conjugation: HIS
Molecular Weight: 11.600kDa inclusive of tags
Source: E. coli
Tissue specificity: Monocytes and lymphocytes.
Form: Lyophilised:Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Filter the product by an appropriate sterile filter before using it in the cell culture.
Purity: by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 50mM Sodium chloride, 20mM Tris, pH 7.5
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities: Belongs to the S-101 family.Contains 2 EF-hand domains.
Gene Name: S100A12 S100 calcium binding protein A12 [ Homo sapiens ]
Official Symbol: S100A12
Synonyms: S100A12; S100 calcium binding protein A12; S100 calcium binding protein A12 (calgranulin C) , S100 calcium binding protein A12 (calgranulin C); protein S100-A12; CAAF1; CAGC; CGRP; ENRAGE; MRP6; p6;
Gene ID: 6283
mRNA Refseq: NM_005621
Protein Refseq: NP_005612
MIM: 603112
Uniprot ID: P80511
Chromosome Location: 1q21
Pathway: Activated TLR4 signalling, organism-specific biosystem; Advanced glycosylation endproduct receptor signaling, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88 cascade initiated on plasma membrane, organism-specific biosystem;
Function: RAGE receptor binding; RAGE receptor binding; calcium ion binding; protein binding; zinc ion binding;

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