"Il3ra" Related Products

Recombinant Mouse Interleukin 3 Receptor, Alpha Chain

Cat. No.: Il3ra-1755M
Description: Interleukin 3 receptor, alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123), is a human gene. The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3.
Molecular Weight: The predicted molecular weight of Recombinant Mouse IL-3 Rα is Mr 61.0 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 70-80 kDa.
Source: Sf 21 Insect Cells.
State Of Matter: Lyophilized.
Purity: >90% by SDS Page and analyzed by silver stain.
Endotoxin: <0.1 ng per 1 µg as determined by the LAL method.
Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°Cto -70°C. After aseptic reconstitution, this protein may be stored at 2°Cto 8°Cfor one month or at -20°Cto -70°Cin a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name: Il3ra interleukin 3 receptor, alpha chain [ Mus musculus ]
Synonyms: Il3ra; interleukin 3 receptor, alpha chain; CD123; SUT-1; CDw123; Il-3 alpha subunit; IL-3 receptor alpha chain; IL-3 receptor alpha SP2 isoform
Gene ID: 16188
mRNA Refseq: NM_008369
Protein Refseq: NP_032395
UniProt ID: P26952
Chromosome Location: 14 A2; 14 1.5 cM
Pathway: Apoptosis; Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Jak-STAT signaling pathway
Function: cytokine receptor activity; receptor activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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