Recombinant Human PDE1B, GST-tagged

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Recombinant Human PDE1B, GST-tagged

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Cat. No. : PDE1B-442H
Product Overview : Recombinant Human PDE1B, full length with N-terminal GST tag expressed in aBaculovirusinfected Sf9 cell expression system. MW= 87 kDa.
Description : Cone cGMP-specific 3",5"-cyclic phosphodiesterase 1B is an enzyme that in humans is encoded by the PDE1B gene.
Source : Baculovirus infected Sf9 cell.
Purity : >70%.
Application : Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Formulated In : 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 20% glycerol, and 3 mM DTT.
Stability : >6 months at –80°C.
PDB rendering based on 1taz. :

Gene Name : PDE1B phosphodiesterase 1B, calmodulin-dependent [ Homo sapiens ]
Synonyms : PDE1B; phosphodiesterase 1B, calmodulin-dependent; PDE1B1; PDES1B; EC 3.1.4.17; Phosphodiesterase-1B; phosphodiesterase IB, calmodulin-dependent; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B; Calcium/calmodulin-dependent 3",5"-cyclic nucleotide phosphodiesterase 1B; Cam-PDE 1B; 63 kDa Cam-PDE
Gene ID : 5153
mRNA Refseq : NM_000924
Protein Refseq : NP_000915
MIM : 171891
UniProt ID : Q01064
Chromosome Location : 12q13
Pathway : Calcium signaling pathway; Progesterone-mediated oocyte maturation; Purine metabolism; Opioid Signalling; Opioid Signalling; Signaling by GPCR; Signalling by NGF
Function : calmodulin binding; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; hydrolase activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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