Recombinant Human ULK1, FLAG-tagged

• Cat.No.: ULK1-31666TH
• Product Overview: Recombinant full length Human ULK1 with N-terminal Flag tag expressed in FreeStyle 293-F cells; MWt 113 kDa.

Specification

• Description: Serine/threonine-protein kinase ULK1 is an enzyme that in humans is encoded by the ULK1 gene.
• Protein length: 1049 amino acids
• Conjugation: FLAG
• Molecular Weight: 113.000kDa inclusive of tags
• Tissue specificity: Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride,pH 7.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.Contains 1 protein kinase domain.

Gene Information

• Gene Name: ULK1 unc-51-like kinase 1 (C. elegans) [ Homo sapiens ]
• Official Symbol: ULK1
• Synonyms: ULK1; unc-51-like kinase 1 (C. elegans); unc 51 (C. elegans) like kinase 1; serine/threonine-protein kinase ULK1; ATG1; ATG1 autophagy related 1 homolog (S. cerevisiae); ATG1A
• Gene ID: 8408
• mRNA Refseq: NM_003565
• Protein Refseq: NP_003556
• MIM: 603168
• Uniprot ID: O75385
• Chromosome Location: 12q24.3
• Pathway: Regulation of autophagy, organism-specific biosystem; Regulation of autophagy, conserved biosystem; Senescence and Autophagy, organism-specific biosystem; mTOR signaling pathway, organism-specific biosystem; mTOR signaling pathway, conserved biosystem
• Function: ATP binding; nucleotide binding; protein binding; protein complex binding; protein serine/threonine kinase activity