Recombinant Human Transthyretin

• Cat.No.: TTR-1837H
• Product Overview: Recombinant human Prealbumin was expressed inE.coliand purified by using conventional chromatography. MW = 13.8 kDa (128aa).

Specification

• Cat. No.: TTR-1837H
• Description: Prealbumin, also known Transthyretin, is a tetrameric human plasma protein that is synthesized mainly in the liver. This protein transports the thyroid hormone thyroxine (T4) and retinol (Vitamin A). It is the best indicator of protein-energy malnutrition because it has a circulating half life of 2 days and responds rapidly to changes in nutritional status. Also point-mutations of its gene are known to be associated with the amyloid diseases senile systemic amyloidosis (SSA), familial amyloid polyneuropathy (FAP), and familial amyloid cardiomyopathy (FAC).
• Source: E.coli.
• Form: Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol.
• Purity: > 95% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGPTGTGESK CPLMVKVLDA VRGSPAINVA VHVFRKAADD TWEPFASGKT SESGELHGLT TEEEFVEGIY KVEIDTKSYW KALGISPFHEHAEVVFTAND SGPRRYTIAA LLSPYSYSTT AVVTNPKE.
• Storage: can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: TTR transthyretin [ Homo sapiens ]
• Synonyms: Transthyretin; PALB; TBPA; HsT2651; TTR; ATTR; thyroxine-binding prealbumin; prealbumin, amyloidosis type I; Prealbumin
• Gene ID: 7276
• mRNA Refseq: NM_000371
• Protein Refseq: NP_000362
• MIM: 176300
• UniProt ID: P02766
• Chromosome Location: 18q12.1
• Function: hormone activity; protein binding