Recombinant Human Ephrin-A1, Fc Chimera


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Recombinant Human Ephrin-A1, Fc Chimera

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Cat. No. : EFNA1-2060H
Product Overview : Recombinant Human Ephrin A1 (C-terminus fused with human IgG1 Fc) produced inmammalian cellscontains 416 amino acids with predicted MW 47.53 KD x 2 (dimmer), and 10 cysteines (Fc has 6).It also has 1 N-link glycosylation site with MW increase up to 5 KD.
Description : Human Ephrin A1 binds to the receptor tyrosine kinase EphA2, EphA4, EphA5, EphA6 and EphA7. Also binds with low affinity to EphA1. Ephrins are a family of molecules which bind to tyrosine kinase receptor Eph. The Eph receptor and their membrane-attached ligands, ephrins, show diverse expression patterns during development. The crucial roles of Eph and ephrins during development suggest involvement of these genes in congenital disorders affecting the nervous system and other tissues. Eph receptors and ephrins may be involved in carcinogenesis.
Source/Host : mammalian cells.
Purity : >90%.
Availability : back order, one month for production.
Recommended Storage Temperature : -70°C.
Gene Name : EFNA1 ephrin-A1 [ Homo sapiens ]
Synonyms : EFNA1; B61; ECKLG; EFL1; EPLG1; LERK-1; TNFAIP4; Ephrin-A1; OTTHUMP00000033242; OTTHUMP00000033271; EPH-related receptor tyrosine kinase ligand 1; Immediate early response protein B61; Tumor necrosis factor, alpha-induced protein 4; Ligand of eph-related kinase 1
Gene ID : 1942
mRNA Refseq : NM_004428
Protein Refseq : NP_004419
MIM : 191164
UniProt ID : P20827
Chromosome Location : 1q21-q22
Pathway : Axon guidance
Function : Ephrin receptor binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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