Recombinant Human Arginase, Liver ARG1-594H

Recombinant Human Arginase, Liver

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Recombinant Human Arginase, Liver

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Cat. No. : ARG1-594H
Product Overview : Recombinant full length human arginase I protein produced inE. coli.
Description : Arginase is the fifth and final step in the urea cycle, a series of biophysical reactions in mammals during which the body disposes of harmful ammonia. Specifically, arginase converts L-arginine into L-ornithine and urea.[1] In most mammals, two isozymes of this enzyme exist; the first, Arginase I, functions in the urea cycle, and is located primarily in the cytoplasm of the liver.
Source : E. coli.
Purity : ≥90% (SDS-PAGE).
Formulation : Liquid. In 10mM TRIS-HCl, pH 7.5, containing 1mM β-mercaptoethanol, 1mM MnCl2 and 50% glycerol.
Specific Activity : ±2.0U/µg protein. One unit is defined as the amount of enzyme that converts 1µmol of L-arginine to L-ornithine and urea per min. at 37°C, pH 9.5 (R.T. Schminke, et al.; J. Biol. Chem. 238, 1012 (1962)).
Storage : -80°C.
Pathways : Arginine and proline metabolism; Metabolic pathways; Metabolism of amino acids and derivatives
ArginasePDB 1CEV :

Gene Name : ARG1 arginase, liver [ Homo sapiens ]
Synonyms : arginase, liver; ARG1; arginase-1; arginase 1; type I arginase; liver-type arginase; EC 3.5.3.1; Type I arginase; Liver-type arginase
Gene ID : 383
mRNA Refseq : NM_000045
Protein Refseq : NP_000036
MIM : 608313
UniProt ID : P05089
Chromosome Location : 6q23
Function : arginase activity; hydrolase activity; metal ion binding

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