Recombinant Human Arginase, Liver

• Cat.No.: ARG1-594H
• Product Overview: Recombinant full length human arginase I protein produced inE. coli.

Specification

• Cat. No.: ARG1-594H
• Description: Arginase is the fifth and final step in the urea cycle, a series of biophysical reactions in mammals during which the body disposes of harmful ammonia. Specifically, arginase converts L-arginine into L-ornithine and urea.[1] In most mammals, two isozymes of this enzyme exist; the first, Arginase I, functions in the urea cycle, and is located primarily in the cytoplasm of the liver.
• Source: E. coli.
• Purity: ≥90% (SDS-PAGE).
• Formulation: Liquid. In 10mM TRIS-HCl, pH 7.5, containing 1mM β-mercaptoethanol, 1mM MnCl2 and 50% glycerol.
• Specific Activity: ±2.0U/µg protein. One unit is defined as the amount of enzyme that converts 1µmol of L-arginine to L-ornithine and urea per min. at 37°C, pH 9.5 (R.T. Schminke, et al.; J. Biol. Chem. 238, 1012 (1962)).
• Storage: -80°C.
• Pathways: Arginine and proline metabolism; Metabolic pathways; Metabolism of amino acids and derivatives

Gene Information

• Gene Name: ARG1 arginase, liver [ Homo sapiens ]
• Synonyms: arginase, liver; ARG1; arginase-1; arginase 1; type I arginase; liver-type arginase; EC 3.5.3.1; Type I arginase; Liver-type arginase
• Gene ID: 383
• mRNA Refseq: NM_000045
• Protein Refseq: NP_000036
• MIM: 608313
• UniProt ID: P05089
• Chromosome Location: 6q23
• Function: arginase activity; hydrolase activity; metal ion binding