Mouse Anti-Mouse A2M Polyclonal Antibody
Cat.No. : | CPBT-27113MM |
Product Overview : | Mouse Polyclonal antibody to Mouse A2M. |
- Specification
- Gene Information
- Related Products
Antigen Description : | Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A- |
Isotype : | IgG |
Immunogen : | Synthetic peptide: KAITYLNTGY QRQLNYKHRD GSYSTFGDKP GRSHANTWLT, corresponding to amino acids 1003/1042 of Mouse alpha 2 Macroglobulin |
Host : | Mouse |
Species : | Mouse |
Specificity : | Secreted in plasma. |
Formulation : | Liquid |
Purity Detail : | Whole antiserum |
Applications : | WB |
Storage buffer : | Preservative: None Constituents: 50% Glycerol, Whole serum |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequence similarities : | Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. |
Gene Name : | A2m alpha-2-macroglobulin [ Mus musculus ] |
Official Symbol : | A2M |
Synonyms : | A2M; alpha-2-macroglobulin; alpha-2-macroglobulin-P; A2M; A2MG_HUMAN; Alpha 2 M; Alpha 2M; Alpha-2-M; Alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; DKFZp779B086; FWP007; S863 7; A2mp; |
Gene ID : | 232345 |
mRNA Refseq : | NM_175628 |
Protein Refseq : | NP_783327 |
Pathway : | Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; |
Function : | endopeptidase inhibitor activity; enzyme binding; growth factor binding; interleukin-1 binding; interleukin-8 binding; |
Products Types
◆ Native Protein | ||
A2m-367M | Native Mouse Alpha-2-Macroglobulin | +Inquiry |
A2m-695R | Native Rat Alpha-2-Macroglobulin | +Inquiry |
◆ Lysates | ||
A2M-593HCL | Recombinant Human A2M cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionIt play an important role in the immune system, binding and neutralizing viruses, bacteria, reducing inflammation, and participating in immune regulation.
Studies of the A2M protein in lung disease have shown that it may work by inhibiting inflammation and reducing lung tissue damage.
The expression of A2M protein in organs or tissues such as liver, kidney, and lymphoid tissue is high.
Proteins eventually clear harmful proteins by capturing and binding to harmful proteins and then entering the cell through internalization.
A2M proteins show potential therapeutic targets in cardiovascular diseases and may have effects on cardiovascular diseases by modulating inflammatory responses and blood clotting.
A2M proteins are studied in many neurological diseases, such as Parkinson's disease, stroke, etc., and may be involved in processes such as inflammation and oxidative stress.
Customer Reviews (3)
Write a reviewIt can be seen that the production process of A2M pays great attention to purity and biological activity, which makes its products have extremely high application value.
Short half-life and high clearance of A2M make them more suitable for use in emergency medical situations and provide more treatment options for patients.
The production process of A2M achieves efficient use of energy, reduces energy consumption, reduces carbon emissions, and is very environmentally friendly.
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