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Mouse Anti-Mouse A2M Polyclonal Antibody

Cat.No. : CPBT-27113MM
Product Overview : Mouse Polyclonal antibody to Mouse A2M.
  • Specification
  • Gene Information
  • Related Products
Antigen Description : Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-
Isotype : IgG
Immunogen : Synthetic peptide: KAITYLNTGY QRQLNYKHRD GSYSTFGDKP GRSHANTWLT, corresponding to amino acids 1003/1042 of Mouse alpha 2 Macroglobulin
Host : Mouse
Species : Mouse
Specificity : Secreted in plasma.
Formulation : Liquid
Purity Detail : Whole antiserum
Applications : WB
Storage buffer : Preservative: None Constituents: 50% Glycerol, Whole serum
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequence similarities : Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
Gene Name : A2m alpha-2-macroglobulin [ Mus musculus ]
Official Symbol : A2M
Synonyms : A2M; alpha-2-macroglobulin; alpha-2-macroglobulin-P; A2M; A2MG_HUMAN; Alpha 2 M; Alpha 2M; Alpha-2-M; Alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; DKFZp779B086; FWP007; S863 7; A2mp;
Gene ID : 232345
mRNA Refseq : NM_175628
Protein Refseq : NP_783327
Pathway : Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem;
Function : endopeptidase inhibitor activity; enzyme binding; growth factor binding; interleukin-1 binding; interleukin-8 binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What role does A2M protein play in the immune system? 12/18/2022

It play an important role in the immune system, binding and neutralizing viruses, bacteria, reducing inflammation, and participating in immune regulation.

What is the relationship between A2M protein and lung disease? 09/29/2022

Studies of the A2M protein in lung disease have shown that it may work by inhibiting inflammation and reducing lung tissue damage.

In which organs or tissues are A2M proteins expressed high? 08/12/2021

The expression of A2M protein in organs or tissues such as liver, kidney, and lymphoid tissue is high.

How does A2M protein remove harmful proteins from the body? 10/14/2020

Proteins eventually clear harmful proteins by capturing and binding to harmful proteins and then entering the cell through internalization.

Can A2M protein be used as a potential therapeutic target for cardiovascular disease? 06/13/2020

A2M proteins show potential therapeutic targets in cardiovascular diseases and may have effects on cardiovascular diseases by modulating inflammatory responses and blood clotting.

In which neurological diseases are A2M proteins studied? 10/30/2019

A2M proteins are studied in many neurological diseases, such as Parkinson's disease, stroke, etc., and may be involved in processes such as inflammation and oxidative stress.

Customer Reviews (3)

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Reviews
04/19/2022

    It can be seen that the production process of A2M pays great attention to purity and biological activity, which makes its products have extremely high application value.

    05/23/2020

      Short half-life and high clearance of A2M make them more suitable for use in emergency medical situations and provide more treatment options for patients.

      03/09/2020

        The production process of A2M achieves efficient use of energy, reduces energy consumption, reduces carbon emissions, and is very environmentally friendly.

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