Recombinant Human Transforming Growth Factor Beta 2
Cat.No. : | TGFB2-438H |
Product Overview : | Recombinant Human Transforming Growth Factor Beta 2 is expressed inE. coli. |
- Specification
- Gene Information
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Cat. No. : | TGFB2-438H |
Description : | Transforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This cytokine is produced in a human cell expression system with serum-free, chemically defined media. |
Source : | E. coli. |
Purity : | >98% pure as demonstrated by SDS-gel electrophoresis and reverse phase HPLC. |
Molecular Weight : | 35.8 kDa. |
Presentation : | Solution containing 50 mM TRIS, 100 mM NaCl, 1% BSA, 0.02% Sodium Azide, pH 7.4. |
Biological Activity : | Annexin V exhibits anti-phospholipase activity and binds to phosphatidylserine (PS). |
Application : | FITC labelling allows simple direct detection of PS by FACS analysis. Counterstaining by propidium iodide allows the discrimination of apoptotic cells. |
Storage : | Stable at 2°-8°C as indicated on the label. Do not freeze! |
Gene Name : | TGFB2 transforming growth factor, beta 2 [ Homo sapiens ] |
Synonyms : | TGFB2; Transforming growth factor beta 2; MGC116892; TGF-beta2; Transforming growth factor beta-2; TGF-beta-2; Glioblastoma-derived T-cell suppressor factor; G-TSF; BSC-1 cell growth inhibitor; Polyergin; Cetermin |
Gene ID : | 7042 |
mRNA Refseq : | NM_001135599 |
Protein Refseq : | NP_001129071 |
MIM : | 190220 |
UniProt ID : | P61812 |
Chromosome Location : | 1q41 |
Pathway : | Cell cycle; Chronic myeloid leukemia; Colorectal cancer; Cytokine-cytokine receptor interaction; Renal cell carcinoma; Hypertrophic cardiomyopathy (HCM); MAPK signaling pathway; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; TGF-beta signaling pathway |
Function : | beta-amyloid binding; cytokine activity; growth factor activity; protein heterodimerization activity; protein homodimerization activity; receptor signaling protein serine/threonine kinase activity; type II transforming growth factor beta receptor binding |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionIt can promote wound healing and tissue repair by stimulating the proliferation and migration of fibroblasts and epithelial cells, as well as promoting collagen synthesis.
Inhibitors or activators targeting TGFB2 may have potential applications for the treatment of a variety of diseases, including cancer, inflammatory diseases, autoimmune diseases, etc.
TGFB2 can regulate cell proliferation and differentiation by binding to its receptor and activating downstream signal transduction pathways.
This protein can be used as an immunomodulator to participate in the differentiation and function of immune cells, as well as the regulation of inflammatory responses.
The expression level of TGFB2 is regulated by a variety of factors, including transcription factors, signal transduction pathways, and epigenetic modifications.
TGFB2 has a variety of associations with other proteins and cytokines. For example, it may interact with vascular endothelial growth factor (VEGF) and be involved in angiogenesis, and may also interact with apoptosis-related proteins to regulate the apoptotic process.
Customer Reviews (3)
Write a reviewNo complicated experimental steps, suitable for beginners.
Excellent performance in Western blot, even if stored for a long time will not affect its performance.
The endotoxin levels were low enough not to interfere with the results.
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