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Recombinant Human Transforming Growth Factor Beta 2

Cat.No. : TGFB2-438H
Product Overview : Recombinant Human Transforming Growth Factor Beta 2 is expressed inE. coli.
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  • Gene Information
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Cat. No. : TGFB2-438H
Description : Transforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This cytokine is produced in a human cell expression system with serum-free, chemically defined media.
Source : E. coli.
Purity : >98% pure as demonstrated by SDS-gel electrophoresis and reverse phase HPLC.
Molecular Weight : 35.8 kDa.
Presentation : Solution containing 50 mM TRIS, 100 mM NaCl, 1% BSA, 0.02% Sodium Azide, pH 7.4.
Biological Activity : Annexin V exhibits anti-phospholipase activity and binds to phosphatidylserine (PS).
Application : FITC labelling allows simple direct detection of PS by FACS analysis. Counterstaining by propidium iodide allows the discrimination of apoptotic cells.
Storage : Stable at 2°-8°C as indicated on the label. Do not freeze!
Gene Name : TGFB2 transforming growth factor, beta 2 [ Homo sapiens ]
Synonyms :
TGFB2; Transforming growth factor beta 2; MGC116892; TGF-beta2; Transforming growth factor beta-2; TGF-beta-2; Glioblastoma-derived T-cell suppressor factor; G-TSF; BSC-1 cell growth inhibitor; Polyergin; Cetermin
Gene ID : 7042
mRNA Refseq : NM_001135599
Protein Refseq : NP_001129071
MIM : 190220
UniProt ID : P61812
Chromosome Location : 1q41
Pathway : Cell cycle; Chronic myeloid leukemia; Colorectal cancer; Cytokine-cytokine receptor interaction; Renal cell carcinoma; Hypertrophic cardiomyopathy (HCM); MAPK signaling pathway; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; TGF-beta signaling pathway
Function : beta-amyloid binding; cytokine activity; growth factor activity; protein heterodimerization activity; protein homodimerization activity; receptor signaling protein serine/threonine kinase activity; type II transforming growth factor beta receptor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the role of TGFB2 in wound healing and tissue repair? 05/16/2022

It can promote wound healing and tissue repair by stimulating the proliferation and migration of fibroblasts and epithelial cells, as well as promoting collagen synthesis.

Are there potential applications for TGFB2 inhibitors or activators? 02/12/2022

Inhibitors or activators targeting TGFB2 may have potential applications for the treatment of a variety of diseases, including cancer, inflammatory diseases, autoimmune diseases, etc.

How does TGFB2 regulate cell proliferation and differentiation? 10/15/2021

TGFB2 can regulate cell proliferation and differentiation by binding to its receptor and activating downstream signal transduction pathways.

What is the relationship between TGFB2 and immune regulation? 03/28/2021

This protein can be used as an immunomodulator to participate in the differentiation and function of immune cells, as well as the regulation of inflammatory responses.

How is the expression level of TGFB2 regulated? 11/03/2020

The expression level of TGFB2 is regulated by a variety of factors, including transcription factors, signal transduction pathways, and epigenetic modifications.

What is the association of TGFB2 with other proteins or cytokines? 09/17/2020

TGFB2 has a variety of associations with other proteins and cytokines. For example, it may interact with vascular endothelial growth factor (VEGF) and be involved in angiogenesis, and may also interact with apoptosis-related proteins to regulate the apoptotic process.

Customer Reviews (3)

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Reviews
11/19/2022

    No complicated experimental steps, suitable for beginners.

    06/28/2022

      Excellent performance in Western blot, even if stored for a long time will not affect its performance.

      07/18/2021

        The endotoxin levels were low enough not to interfere with the results.

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