Recombinant Equine Interleukin 5 (Colony-Stimulating Factor, Eosinophil)

• Cat.No.: IL5-257E
• Product Overview: Recombinant Equine IL-5 was expressed inYeast. MW= 12.9 kDa (114 aa).

Specification

• Species: Equine
• Source: Yeast
• Tag: Non
• Description: Interleukin 5 (IL-5) plays an important role in B cell development by inducing the terminal differentiation of late-developing B cells. Additionally, IL-5 regulates the differentiation, survival and degranulation of eosinophils. IL-5 is expressed predominately by T-lymphocytes and mast cells, and to a lesser extent by eosinophils, natural killer cells and endothelial cells.
• Formulation/ Reconstitution: Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
• Purification: Ion-exchange chromatography.
• Purity: >95% as visualized by SDS-PAGE analysis.
• Amino Acid Sequence: AVESPMNRLV AETLTLLSTH RTLLIGDGNL MIPTPEHKNH QLCIEEVFQG IDTLKNQTVQ GDAVAKLFQN LSLIKGYIDL QKKKCGGERW RVKQFLDYLQ EFLGVINTEW TIEG.
• Bioactivity: In testing.
• Stability And Storage: Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Equus caballus ]
• Synonyms: interleukin 5 (colony-stimulating factor, eosinophil); IL5; IL-5; interleukin 5; TRF; T-cell replacing factor; interleukin-5; eosinophil differentiation factor
• Gene ID: 100034199
• mRNA Refseq: NM_001082499.1
• Protein Refseq: NP_001075968.1
• UniProt ID: O02699
• Chromosome Location: 14
• Pathway: Allograft rejection; Asthma; Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; Hematopoietic cell lineage; Intestinal immune network for IgA production; Jak-STAT signaling pathway; T cell receptor signaling pathway