Recombinant Equine Interleukin 5 (Colony-Stimulating Factor, Eosinophil) IL5-257E

Recombinant Equine Interleukin 5 (Colony-Stimulating Factor, Eosinophil)

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Recombinant Equine Interleukin 5 (Colony-Stimulating Factor, Eosinophil)

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Cat. No. : IL5-257E
Product Overview : Recombinant Equine IL-5 was expressed inYeast. MW= 12.9 kDa (114 aa).
Description : Interleukin 5 (IL-5) plays an important role in B cell development by inducing the terminal differentiation of late-developing B cells. Additionally, IL-5 regulates the differentiation, survival and degranulation of eosinophils. IL-5 is expressed predominately by T-lymphocytes and mast cells, and to a lesser extent by eosinophils, natural killer cells and endothelial cells.
Source : Yeast.
Formulation/ Reconstitution : Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Purification : Ion-exchange chromatography.
Purity : >95% as visualized by SDS-PAGE analysis.
Amino Acid Sequence : AVESPMNRLV AETLTLLSTH RTLLIGDGNL MIPTPEHKNH QLCIEEVFQG IDTLKNQTVQ GDAVAKLFQN LSLIKGYIDL QKKKCGGERW RVKQFLDYLQ EFLGVINTEW TIEG.
Bioactivity : In testing.
Stability And Storage : Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Gene Name : IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Equus caballus ]
Synonyms : interleukin 5 (colony-stimulating factor, eosinophil); IL5; IL-5; interleukin 5; TRF; T-cell replacing factor; interleukin-5; eosinophil differentiation factor
Gene ID : 100034199
mRNA Refseq : NM_001082499.1
Protein Refseq : NP_001075968.1
UniProt ID : O02699
Chromosome Location : 14
Pathway : Allograft rejection; Asthma; Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; Hematopoietic cell lineage; Intestinal immune network for IgA production; Jak-STAT signaling pathway; T cell receptor signaling pathway

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