"PLK4" Related Products

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Recombinant Human Polo-like Kinase 4, GST-His

Cat. No. : PLK4-705H
Product Overview : Recombinant Human PLK4, full length, amino acids M1-H970, N-terminally fused to GST-HIS6-Thrombin cleavage site, was expressed inSf9insect cells.MW = 138,568 Da.
Description : This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle.
Source : Baculovirus infected Sf9 cells.
Purification : One-step affinity purification using GSH-agarose.
Product Identity : SAK was confirmed as human SAK by mass spectroscopy LC-ESI-MS/MS (Protagen AG, Germany).
Storage Buffer : 50 mM HEPES, pH 7.5; 100 mM NaCl, 5 mM DTT, 4 mM reduced glutathione, 20% glycerol.
Concentration : 0.050 μg/μl (Bradford method using BSA [Sigma, cat#A-7638, Lot 79H7641] as standard protein)
Specific Activity : 6 pmol/μg×min.
Storage : -80°C. Avoid repeated freeze-thaw cycles!
Gene Name : PLK4 polo-like kinase 4 [ Homo sapiens ]
Synonyms : PLK4; polo-like kinase 4; SAK; STK18; serine/threonine-protein kinase PLK4; PLK-4; Snk akin kinase; serine/threonine kinase 18; serine/threonine-protein kinase 18; serine/threonine protein kinase SAK; serine/threonine-protein kinase Sak; EC 2.7.11.21; polo-like kinase 4 (Drosophila)
Gene ID : 10733
mRNA Refseq : NM_001190799
Protein Refseq : NP_001177728
MIM : 605031
UniProt ID : O00444
Chromosome Location : 4q28
Function : ATP binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; protein tyrosine kinase activity; transferase activity

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