Recombinant Human MAPKAPK5
Cat.No. : | MAPKAPK5-736H |
Product Overview : | Recombinant Human MAPKAPK5, full length, amino acids M1-Q471, activated, untagged, was expressed inE.coli. MW = 54,161 Da. |
- Specification
- Gene Information
- Related Products
Cat. No. : | MAPKAPK5-736H |
Description : | MAP kinase-activated protein kinase 5 is an enzyme that in humans is encoded by the MAPKAPK5 gene.The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. |
Source : | E.coli. |
Purification : | Immobilized Metal Affinity Chromatography. |
Product Identity : | MAPKAPK5 was confirmed as MAPKAPK5 by mass spectroscopy LC-ESI-MS/MS. |
Activation : | with MKK6-SDTD / p38-alpha. |
Storage Buffer : | 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 20% glycerol. |
Concentration : | 0.772 μg/μl (Bradford method using BSA [Sigma, cat# A-7638, Lot 79H7641] as standard protein). |
Specific Activity : | 11 pmol/μg×min. |
Storage : | -80°C. Avoid repeated freeze-thaw cycles! |
Gene Name : | MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 [ Homo sapiens ] |
Synonyms : | MAPKAPK5; mitogen-activated protein kinase-activated protein kinase 5; PRAK; MAP kinase-activated protein kinase 5; MAPKAPK-5; MAPKAP kinase 5; MAPK-activated protein kinase 5; p38-regulated/activated protein kinase; EC 2.7.11.1 |
Gene ID : | 8550 |
mRNA Refseq : | NM_003668 |
Protein Refseq : | NP_003659 |
MIM : | 606723 |
UniProt ID : | Q8IW41 |
Chromosome Location : | 12q24.12-q24.13 |
Pathway : | MAPK signaling pathway |
Function : | ATP binding; MAP kinase kinase activity; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
MAPKAPK5-2495R | Recombinant Rhesus Macaque MAPKAPK5 Protein, His (Fc)-Avi-tagged | +Inquiry |
MAPKAPK5-1303H | Recombinant Human MAPKAPK5 Protein (S2-Q473), Tag Free | +Inquiry |
MAPKAPK5-1304H | Recombinant Human MAPKAPK5 Protein (S2-Q473), GST tagged | +Inquiry |
MAPKAPK5-5358M | Recombinant Mouse MAPKAPK5 Protein, His (Fc)-Avi-tagged | +Inquiry |
MAPKAPK5-567H | Recombinant Human MAPKAPK5 protein, His&GST-tagged | +Inquiry |
◆ Lysates | ||
MAPKAPK5-432HCL | Recombinant Human MAPKAPK5 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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