Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human MAPKAPK5

Cat.No. : MAPKAPK5-736H
Product Overview : Recombinant Human MAPKAPK5, full length, amino acids M1-Q471, activated, untagged, was expressed inE.coli. MW = 54,161 Da.
  • Specification
  • Gene Information
  • Related Products
Cat. No. : MAPKAPK5-736H
Description : MAP kinase-activated protein kinase 5 is an enzyme that in humans is encoded by the MAPKAPK5 gene.The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites.
Source : E.coli.
Purification : Immobilized Metal Affinity Chromatography.
Product Identity : MAPKAPK5 was confirmed as MAPKAPK5 by mass spectroscopy LC-ESI-MS/MS.
Activation : with MKK6-SDTD / p38-alpha.
Storage Buffer : 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 20% glycerol.
Concentration : 0.772 μg/μl (Bradford method using BSA [Sigma, cat# A-7638, Lot 79H7641] as standard protein).
Specific Activity : 11 pmol/μg×min.
Storage : -80°C. Avoid repeated freeze-thaw cycles!
Gene Name : MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 [ Homo sapiens ]
Synonyms : MAPKAPK5; mitogen-activated protein kinase-activated protein kinase 5; PRAK; MAP kinase-activated protein kinase 5; MAPKAPK-5; MAPKAP kinase 5; MAPK-activated protein kinase 5; p38-regulated/activated protein kinase; EC 2.7.11.1
Gene ID : 8550
mRNA Refseq : NM_003668
Protein Refseq : NP_003659
MIM : 606723
UniProt ID : Q8IW41
Chromosome Location : 12q24.12-q24.13
Pathway : MAPK signaling pathway
Function : ATP binding; MAP kinase kinase activity; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All MAPKAPK5 Products

Required fields are marked with *

My Review for All MAPKAPK5 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends