|Product Overview:||Recombinant Human BMP7, Ser293-His431, was produced in CHO cell under cGMP guidelines.|
|Form:||Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.|
|Bio-activity:||Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al. (1999) Exp. Cell Res. 250:351.|
|Molecular Mass:||Predicted Molecular Mass: 15.7 (monomer) kDa
SDS-PAGE: 18-24 kDa, reducing conditions
|N-terminal Sequence Analysis:||Ser-Thr-Gly-Ser-Lys-Gln-Arg-Ser-Gln-Asn|
|Endotoxin:||<0.01 EU per 1 μg of the protein by the LAL method.|
|Purity:||>95%, by SDS-PAGE with silver staining, under reducing conditions.|
|Storage:||Avoid repeated freeze-thaw cycles.
12 months, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
|Reconstitution:||Reconstitute at 100-200 μg/mL in sterile 4 mM HCl.|
|Quality Statement:||Our GMP proteins are produced according to relevant sections of the following documents: WHO TRS, No. 822, 1992 Annex 1, Good Manufacturing Practices for Biological Products; USP Chapter 1043, Ancillary Materials for Cell, Gene and Tissue-Engineered Products and USP Chapter 92, Growth Factors and Cytokines Used in Cell Therapy Manufacturing.|
|Shipping:||The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.|
|Gene Name:||BMP7 bone morphogenetic protein 7 [ Homo sapiens ]|
|Synonyms:||BMP7; bone morphogenetic protein 7; OP 1; osteogenic protein 1; BMP-7; OP-1;|