Active GMP Recombinant Human IL12A Protein
Cat.No. : | IL12A-129HG |
Product Overview : | Recombinant Human IL12B(Ile23–Ser328) and Human IL12A(Arg23–Ser219), was co-produced in Sf 21 (baculovirus)-derived under cGMP guidelines. |
- Specification
- Gene Information
- Related Products
Source : | Insect cell |
Species : | Human |
Form : | Lyophilized from a 0.2 μm filtered solution in PBS. |
Bio-activity : | Measured in a cell proliferation assay using PHA-stimulated human T lymphoblasts. Symons, J.A. et al. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 272. |
Molecular Mass : | Predicted Molecular Mass: 34.7 (p40) & 22.5 (p35) kDa SDS-PAGE: 41 kDa (p40) and 29 kDa (p35), reducing conditions |
N-terminal Sequence Analysis : | Ile-Trp-Glu-Leu-Lys-Lys-Asp-Val-Tyr-Val (p40) Arg-Asn-Leu-Pro-Val-Ala-Thr-Pro-Asp-Pro (p35) |
Endotoxin : | <1.0 EU per 1 μg of the protein by the LAL method. |
Purity : | >97%, by SDS-PAGE with silver staining. |
Storage : | Avoid repeated freeze-thaw cycles. 12 months, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Reconstitution : | Reconstitute at 100 μg/mL in PBS. |
Quality Statement : | Our GMP proteins are produced according to relevant sections of the following documents: WHO TRS, No. 822, 1992 Annex 1, Good Manufacturing Practices for Biological Products; USP Chapter 1043, Ancillary Materials for Cell, Gene and Tissue-Engineered Products and USP Chapter 92, Growth Factors and Cytokines Used in Cell Therapy Manufacturing. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Gene Name : | IL12A interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) [ Homo sapiens ] |
Official Symbol : | IL12A |
Synonyms : | IL12A; NKSF1; interleukin-12 subunit alpha; CLMF; p35; IL 12; subunit p35; IL 12A; IL35 subunit; interleukin 12; interleukin 12 alpha chain; 35 kD subunit; NFSK; CLMF p35; IL-12 subunit p35; IL-12, subunit p35; interleukin 12, p35; P35; IL-12A; |
Gene ID : | 3592 |
mRNA Refseq : | NM_000882 |
Protein Refseq : | NP_000873 |
MIM : | 161560 |
UniProt ID : | P29459 |
Products Types
◆ Recombinant Protein | ||
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IL12A-139H | Recombinant Active Human IL12A Protein, His-tagged(C-ter) | +Inquiry |
IL12A-310H | Recombinant Human IL12A Protein | +Inquiry |
IL12A-062H | Active Recombinant Human IL12 Protein | +Inquiry |
Il12a-086M | Active Recombinant Mouse Il12a Protein | +Inquiry |
◆ Lysates | ||
IL12A-001CCL | Recombinant Cynomolgus IL12A cell lysate | +Inquiry |
IL12A-2435HCL | Recombinant Human IL12A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (10)
Ask a questionMass spectrometry identifies IL12A's post-translational modifications and their roles.
Knockout models validate IL12A's roles in immune response modulation.
Protein footprinting assays reveal IL12A's binding interfaces with receptors.
ELISA and stability assays quantify IL12A secretion and stability in culture.
SPR characterizes IL12A's interactions with antibodies and inhibitors.
Cellular assays gauge IL12A's cytokine induction in immune cells.
Isothermal titration calorimetry measures IL12A's binding affinity with receptors.
Structural biology techniques analyze IL12A genetic variant impacts.
Site-directed mutagenesis probes IL12A's functional domains and interactions.
Bioluminescence imaging tracks IL12A expression dynamics in vivo.
Customer Reviews (3)
Write a reviewSuitable for co-immunoprecipitation.
Consistent in bioactivity.
Good for receptor binding studies.
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