GMP Recombinant Human IL16 protein
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Cat.No. : | IL16-4330HG Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Human IL16 was produced in E. coli using non-animal reagents in an animal-free facility under cGMP guidelines. |
Description : | Human Interleukin-16 (IL-16) is also called lymphocyte chemoattractant factor (LCF) and it has three isoforms which are cleaved from pre-Interleukin-16. IL-16 is mostly secreted by lymphocytes, epithelial cells, eosinophils, and CD8+ T cells. It has many functions including induction of the IL-2Rα on T cells, suppression of human immunodeficiency virus (HIV) replication, inhibition of T-cell antigen receptor/CD3 mediated T-cell stimulation in mixed lymphocyte reactions and so on. It signals through CD4 receptor. Furthermore, recombinant human IL-16 (130 a.a.) contains 130 amino acid residues and it shares 85 % a.a. sequence identity with murine IL-16. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized from a 0.2 µm filtered concentrated solution in 20 mM Tris, 150 mM NaCl, pH 7.0. |
Bio-activity : | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CD4+ T Lymphocytes is in a concentration range of 1.0-100 ng/ml. |
Molecular Mass : | Approximately 13.4 kDa, a single non-glycosylated polypeptide chain containing 130amino acids. |
AA Sequence : | MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS |
Endotoxin : | Less than 1 EU/µg of rHuIL-16, 130 a.a. as determined by LAL method. |
Purity : | > 95 % by SDS-PAGE and HPLC analyses. |
Storage : | This lyophilized preparation is stable at 2-8 centigrade, but should be kept at -20 centigrade for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 centigrade. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 centigrade to -70 centigrade. Avoid repeated freeze/thaw cycles. |
Reconstitution : | Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 centigrade. Further dilutions should be made in appropriate buffered solutions. |
Quality Statement : | Our GMP proteins are produced according to relevant sections of the following documents: WHO TRS, No. 822, 1992 Annex 1, Good Manufacturing Practices for Biological Products; USP Chapter 1043, Ancillary Materials for Cell, Gene and Tissue-Engineered Products and USP Chapter 92, Growth Factors and Cytokines Used in Cell Therapy Manufacturing. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Figure : |
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Gene Name : | IL16 interleukin 16 [ Homo sapiens (human) ] |
Official Symbol : | IL16 |
Synonyms : | LCF; NIL16; PRIL16; prIL-16; Interleukin-16 isoform 2, Lymphocyte chemoattractant factor, LCF |
Gene ID : | 3603 |
mRNA Refseq : | NM_172217.3 |
Protein Refseq : | NP_757366.2 |
MIM : | 603035 |
UniProt ID : | Q14005 |
◆ Recombinant Protein
IL16-136M | Recombinant Mouse IL16 Protein | +Inquiry |
IL16-1165H | Recombinant Human IL16 Protein, His (Fc)-Avi-tagged | +Inquiry |
Il16-1239M | Recombinant Mouse Il16 Protein, MYC/DDK-tagged | +Inquiry |
IL16-1007C | Recombinant Chicken IL16 Protein, His-tagged | +Inquiry |
IL16-3143H | Recombinant Human IL16 Protein, His (Fc)-Avi-tagged | +Inquiry |
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◆ Native Protein
IL16-29736TH | Native Human IL16 | +Inquiry |
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◆ Lysates
IL16-5245HCL | Recombinant Human IL16 293 Cell Lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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