| Description : |
Thrombopoietin is a glycoprotein hormone produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that fragment into large numbers of platelets. |
| Source : |
Escherichia coli |
| Species : |
Porcine |
| Tag : |
His |
| Form : |
Lyophilized |
| AA Sequence : |
APPRLICDSRVLERYILEAKEGENA TMGCAESCSFSENITVPDTKVNFYA WKRMEVQQQAMEVWQGLALLSEAIL QGQALLANSSQPSEALQLHVDKAVS GLRSLTSLLRALGAQKEAIPLPDAS PSSATPLRTFAVDTLCKLFRNYSNF LRGKLTLYTGEACRRRDR with polyhistidine tag at the N-terminus |
| Endotoxin : |
<0.1 EU per 1 μg of the protein by the LAL method. |
| Purity : |
>95% as determined by SDS-PAGE. Ni-NTA chromatography |
| Notes : |
Please use within one month after protein reconstitution. |
| Storage : |
Lyophilized protein should be stored at -20°C. Upon reconstitution, protein aliquots should be stored at -20°C or -80°C. |
| Storage Buffer : |
The protein was lyophilized from a solution containing 1X PBS, pH 7.4. |
| Reconstitution : |
It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
