Native Human COL2A1 Protein

• Cat.No.: COL2A1-1648H
• Product Overview: Human COL2A1 native protein from human nasal septum.

Specification

• Description: This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]
• Source: Human nasal septum
• Species: Human
• Form: Lyophilized
• Applications: SDS-PAGE
• Storage: Store at -20 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: No additive

Gene Information

• Gene Name: COL2A1 collagen, type II, alpha 1 [ Homo sapiens ]
• Official Symbol: COL2A1
• Synonyms: COL2A1; collagen, type II, alpha 1; collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) , SEDC; collagen alpha-1(II) chain; chondrocalcin; cartilage collagen; alpha-1 type II collagen; collagen II, alpha-1 polypeptide; AOM; ANFH; SEDC; COL11A3; MGC131516
• Gene ID: 1280
• mRNA Refseq: NM_001844
• Protein Refseq: NP_001835
• MIM: 120140
• UniProt ID: P02458