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Recombinant Active Human TGFA Protein, His-tagged(C-ter)

Cat.No. : TGFA-297H
Product Overview : Recombinant Active Human TGFA Protein with His tag (C-ter) was expressed in E. coli.
  • Specification
  • Gene Information
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Description : This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Source : E. coli
Species : Human
Tag : His(C-ter)
Form : Powder
Bio-activity : Determined by its ability to induce 3T3 cells proliferation. The ED50 for this effect is < 0.2 ng/mL. The specific activity of recombinant human TGF alpha is > 5 x 10^6 IU/mg.
AA Sequence : MVVSHFNDCPDSHTQFCFHGTCRFL VQEDKPACVCHSGYVGARCEHADLL A
Endotoxin : Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test.
Purity : > 98% (by SDS-PAGE)
Applications : SDS-PAGE
Notes : For laboratory research only, not for drug, diagnostic or other use.
Storage : Lyophilized protein should be stored at -20°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
Storage Buffer : PBS (pH 8.0)
Reconstitution : It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
Gene Name : TGFA transforming growth factor, alpha [ Homo sapiens ]
Official Symbol : TGFA
Synonyms : TGFA; transforming growth factor, alpha; protransforming growth factor alpha; TGF-alpha; TFGA;
Gene ID : 7039
mRNA Refseq : NM_001099691
Protein Refseq : NP_001093161
MIM : 190170
UniProt ID : P01135

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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