Recombinant Dog IL12A Protein, His-tagged
|Product Overview :||Recombinant Dog IL12A Protein (Leu41-Leu186) with His tag was expressed in E. coli.|
- Gene Information
- Related Products
|Description :||This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.|
|Source :||E. coli|
|Form :||Freeze-dried powder|
|Molecular Mass :||Predicted Molecular Mass: 20.1 kDa; Accurate Molecular Mass: 25 kDa|
|Protein length :||Leu41-Leu186|
|Purity :||> 97%|
|Applications :||Positive Control; Immunogen; SDS-PAGE; WB.|
|Stability :||The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.|
|Storage :||Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.|
|Storage Buffer :||PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.|
|Reconstitution :||Reconstitute in PBS or others.|
|Gene Name :||IL12A interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) [ Canis lupus familiaris ]|
|Official Symbol :||IL12A|
|Synonyms :||IL12A; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35); interleukin-12 subunit alpha; IL-12A; CLMF p35; interleukin 12B; IL-12 subunit p35; interleukin-12 p35 subunit; cytotoxic lymphocyte maturation factor 35 kDa subunit;|
|Gene ID :||403977|
|mRNA Refseq :||NM_001003293|
|Protein Refseq :||NP_001003293|
|UniProt ID :||Q28267|
|◆ Recombinant Protein|
|IL12A-2680R||Recombinant Rat IL12A Protein, His (Fc)-Avi-tagged||+Inquiry|
|IL12A-4327HG||Recombinant Human IL12A protein||+Inquiry|
|IL12A-139H||Recombinant Active Human IL12A Protein, His-tagged(C-ter)||+Inquiry|
|IL12A-062H||Recombinant Human IL12 Protein||+Inquiry|
|IL12A-25H||Recombinant Human IL12 Protein, Animal Free||+Inquiry|
|IL12A-2435HCL||Recombinant Human IL12A cell lysate||+Inquiry|
|IL12A-001CCL||Recombinant Cynomolgus IL12A cell lysate||+Inquiry|
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (10)Ask a question
Mass spectrometry identifies IL12A's post-translational modifications and their roles.
Knockout models validate IL12A's roles in immune response modulation.
Protein footprinting assays reveal IL12A's binding interfaces with receptors.
ELISA and stability assays quantify IL12A secretion and stability in culture.
SPR characterizes IL12A's interactions with antibodies and inhibitors.
Cellular assays gauge IL12A's cytokine induction in immune cells.
Isothermal titration calorimetry measures IL12A's binding affinity with receptors.
Structural biology techniques analyze IL12A genetic variant impacts.
Site-directed mutagenesis probes IL12A's functional domains and interactions.
Bioluminescence imaging tracks IL12A expression dynamics in vivo.
Customer Reviews (3)Write a review
Suitable for co-immunoprecipitation. -
Consistent in bioactivity. -
Good for receptor binding studies. -
Ask a Question for All IL12A Products
Required fields are marked with *
My Review for All IL12A Products
Required fields are marked with *