Recombinant Full Length Human ADAM2 Protein, GST-tagged

• Cat.No.: ADAM2-871HF
• Product Overview: Human ADAM2 full-length ORF ( AAH34957.1, 1 a.a. - 716 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 104.39 kDa
• Protein Length: 716 amino acids
• AA Sequence: MWRVLFLLSG LGGLRMDSNF DSLPVQITVP EKIRSIIKEG IESQASYKIV IEGKPYTVNL MQKNFLPHNF RVYSYSGTGI MKPLDQDFQN FCHYQGYIEG YPKSVVMVST CTGLRGVLQF ENVSYGIEPL ESSVGFEHVI YQVKHKKADV SLYNEKDIES RDLSFKLQSV EYNHMGSDTT VVAQKVFQLI GLTNAIFVSF NITIILSSLE LWIDENKIAT TGEANELLHT FLRWKTSYLV LRPHDVAFLL VYREKSNYVG ATFQGKMCDA NYAGGVVLHP RTISLESLAV ILAQLLSLSM GITYDDINKC QCSGAVCIMN PEAIHFSGVK IFSNCSFEDF AHFISKQKSQ CLHNQPRLDP FFKQQAVCGN AKLEAGEECD CGTEQDCALI GETCCDIATC RFKAGSNCAE GPCCENCLFM SKERMCRPSF EECDLPEYCN GSSASCPENH YVQTGHPCGL NQWICIDGVC MSGDKQCTDT FGKEVEFGPS ECYSHLNSKT DVSGNCGISD SGYTQCEADN LQCGKLICKY VGKFLLQIPR ATIIYANISG HLCIAVEFAS DHADSQKMWI KDGTSCGSNK VCRNQRCVSS SYLGYDCTTD KCNDRGVCNN KKHCHCSASY LPPDCSVQSD LWPGGSIDSG NFPPVAIPAR LPERRYIENI YHSKPMRWPF FLFIPFFIIF CVLIAIMVKV NFQRKKWRTE DYSSDEQPES ESEPKG
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ADAM2 ADAM metallopeptidase domain 2 [ Homo sapiens ]
• Official Symbol: ADAM2
• Synonyms: ADAM2; ADAM metallopeptidase domain 2; fertilin beta , FTNB; disintegrin and metalloproteinase domain-containing protein 2; cancer/testis antigen 15; CT15; PH 30b; PH30; PH-30; ADAM 2; PH30-beta; fertilin beta; fertilin subunit beta; FTNB; CRYN1; CRYN2; PH-30b
• Gene ID: 2515
• mRNA Refseq: NM_001464
• Protein Refseq: NP_001455
• MIM: 601533
• UniProt ID: Q99965