Recombinant Full Length Human CD4 Protein, GST-tagged

• Cat.No.: CD4-3184HF
• Product Overview: Human CD4 full-length ORF (AAH25782, 1 a.a. - 458 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 76.12 kDa
• Protein length: 458 amino acids
• AA Sequence: MNRGVPFRHLLLVLQLALLPAATQG KKVVLGKKGDTVELTCTASQKKSIQ FHWKNSNQIKILGNQGSFLTKGPSK LNDRADSRRSLWDQGNFPLIIKNLK IEDSDTYICEVEDQKEEVQLLVFGL TANSDTHLLQGQSLTLTLESPPGSS PSVQCRSPRGKNIQGGKTLSVSQLE LQDSGTWTCTVLQNQKKVEFKIDIV VLAFQKASSIVYKKEGEQVEFSFPL AFTVEKLTGSGELWWQAERASSSKS WITFDLKNKEVSVKRVTQDPKLQMG KKLPLHLTLPQALPQYAGSGNLTLA LEAKTGKLHQEVNLVVMRATQLQKN LTCEVWGPTSPKLMLSLKLENKEAK VSKREKAVWVLNPEAGMWQCLLSDS GQVLLESNIKVLPTWSTPVQPMALI VLGGVAGLLLFIGLGIFFCVRCRHR RRQAERMSQIKRLLSEKKTCQCPHR FQKTCSPI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CD4 CD4 molecule [ Homo sapiens ]
• Official Symbol: CD4
• Synonyms: CD4; CD4 molecule; CD4 antigen (p55), T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut
• Gene ID: 920
• mRNA Refseq: NM_000616
• Protein Refseq: NP_000607
• MIM: 186940
• UniProt ID: P01730

Reviews

01/08/2031

The CD4 proteins purchased from your company is suitable for ELISA.

02/06/2023

Protein products are put into experiments with good effect and reliable experimental results.

01/22/2022

The technical expert will follow up on the progress of my experiments and provide constructive advice on the problems that arise in my experiments.

Q&As

What is the connection between CD4 and glycoprotein GP120?

CD4 binds to glycoprotein GP120.

Where is CD4 primarily expressed?

CD4 is mainly expressed in T cells and thymocytes.

Where is CD4 localized?

CD4 is localized in the cell membrane.