Recombinant Full Length Human RCC1 Protein, C-Flag-tagged

• Cat.No.: RCC1-738HFL
• Product Overview: Recombinant Full Length Human RCC1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Enables several functions, including guanyl-nucleotide exchange factor activity; nucleosomal DNA binding activity; and protein heterodimerization activity. Involved in several processes, including G1/S transition of mitotic cell cycle; regulation of mitotic nuclear division; and spindle organization. Located in chromatin; cytoplasm; and nucleus. Part of protein-containing complex.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 44.8 kDa
• AA Sequence: MSPKRIAKRRSPPADAIPKSKKVKV SHRSHSTEPGLVLTLGQGDVGQLGL GENVMERKKPALVSIPEDVV QAEAGGMHTVCLSKSGQVYSFGCND EGALGRDTSVEGSEMVPGKVELQEK VVQVSAGDSHTAALTDDGRV FLWGSFRDNNGVIGLLEPMKKSMVP VQVQLDVPVVKVASGNDHLVMLTAD GDLYTLGCGEQGQLGRVPEL FANRGGRQGLERLLVPKCVMLKSRG SRGHVRFQDAFCGAYFTFAISHEGH VYGFGLSNYHQLGTPGTESC FIPQNLTSFKNSTKSWVGFSGGQHH TVCMDSEGKAYSLGRAEYGRLGLGE GAEEKSIPTLISRLPAVSSV ACGASVGYAVTKDGRVFAWGMGTNY QLGTGQDEDAWSPVEMMGKQLENRV VLSVSSGGQHTVLLVKDKEQ
  STRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: RCC1 regulator of chromosome condensation 1 [ Homo sapiens (human) ]
• Official Symbol: RCC1
• Synonyms: CHC1; RCC1-I
• Gene ID: 1104
• mRNA Refseq: NM_001269.6
• Protein Refseq: NP_001260.1
• MIM: 179710
• UniProt ID: P18754