Description : |
Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the Full-Length nature of some of them have not been characterized yet. |
Source : |
In Vitro Cell Free System |
Species : |
Human |
Tag : |
GST |
Form : |
50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : |
93.2 kDa |
Protein Length : |
602 amino acids |
AA Sequence : |
MAALAAAAKKVWSARRLLVLLFTPL ALLPVVFALPPKEGRCLFVILLMAV YWCTEALPLSVTALLPIVLFPFMGI LPSNKVCPQYFLDTNFLFLSGLIMA SAIEEWNLHRRIALKILMLVGVQPA RLILGMMVTTSFLSMWLSNTASTAM MLPIANAILKSLFGQKEVRKDPSQE SEENTAAVRRNGLHTVPTEMQFLAS TEAKDHPGETEVPLDLPADSRKEDE YRRNIWKGFLISIPYSASIGGTATL TGTAPNLILLGQLKSFFPQCDVVNF GSWFIFAFPLMLLFLLAGWLWISFL YGGLSFRGWRKNKSEIRTNAEDRAR AVIREEYQNLGPIKFAEQAVFILFC MFAILLFTRDPKFIPGWASLFNPGF LSDAVTGVAIVTILFFFPSQRPSLK WWFDFKAPNTETEPLLTWKKAQETV PWNIILLLGGGFAMAKGCEESGLSV WIGGQLHPLENVPPALAVLLITVVI AFFTEFASNTATIIIFLPVLAELAI RLRVHPLYLMIPGTVGCSFAFMLPV STPPNSIAFASGHLLVKDMVRTGLL MNLMGVLLLSLAMNTWAQTIFQLGT FPDWADMYSVNVTALPPTLANDTFR TL |
Applications : |
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : |
Best use within three months from the date of receipt of this protein |
Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |