Recombinant Human SLC13A3 cell lysate

• Cat.No.: SLC13A3-1615HCL

Specification

• Description: Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 [ Homo sapiens ]
• Official Symbol: SLC13A3
• Synonyms: SLC13A3; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3; solute carrier family 13 member 3; NADC3; SDCT2; hNaDC3; naDC-3; Na(+)/dicarboxylate cotransporter 3; sodium-dependent high affinity dicarboxylate transporter 3; sodium-dependent high-affinity dicarboxylate transporter 2
• Gene ID: 64849
• mRNA Refseq: NM_001011554
• Protein Refseq: NP_001011554
• MIM: 606411
• UniProt ID: Q8WWT9
• Chromosome Location: 20q12-q13.1
• Pathway: SLC-mediated transmembrane transport, organism-specific biosystem; Sodium-coupled sulphate, di- and tri-carboxylate transporters, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds, organism-specific biosystem
• Function: L-aspartate transmembrane transporter activity; citrate transmembrane transporter activity; high affinity sodium:dicarboxylate symporter activity; succinate transmembrane transporter activity; symporter activity; transporter activity