Active Recombinant Human/Cynomolgus ACVR2B protein, hFc-Avi-tagged, Biotinylated, Low Endotoxin

• Cat.No.: ACVR2B-2392H
• Product Overview: Biotinylated Recombinant Human/Cynomolgus ACVR2B protein(Q13705-1(Human) / XP_045242398.1(Cynomolgus))(19-137 aa(Human) / 40-158 aa(Cynomolgus)), fused with C-terminal hFc and Avi tag, was expressed in HEK293.

Specification

• Species: Human/Cynomolgus
• Source: HEK293
• Tag: Avi
• Protein Length: 19-137 aa(Human) / 40-158 aa(Cynomolgus)
• Conjugation/Label: Biotin
• Form: Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Bio-activity: Immobilized Human Activin A, No Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human/Cynomolgus Activin RIIB, hFc Tag with the EC50 of 20.9ng/ml determined by ELISA.
• Molecular Mass: The protein has a predicted MW of 41.41 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 0.01 EU per μg by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: Store at -20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
• Reconstitution: Dissolve the lyophilized protein in distilled water.

Gene Information

• Gene Name: ACVR2B activin A receptor, type IIB [ Homo sapiens ]
• Official Symbol: ACVR2B
• Synonyms: ACVR2B; activin A receptor, type IIB; activin receptor type-2B; ActR IIB; HTX4; ACTRIIB; ActR-IIB
• Gene ID: 93
• mRNA Refseq: NM_001106
• Protein Refseq: NP_001097
• MIM: 602730
• UniProt ID: Q13705