Recombinant Human ALAD Protein, GST-tagged
Cat.No. : | ALAD-428H |
Product Overview : | Human ALAD full-length ORF ( NP_000022.2, 1 a.a. - 339 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 63.6 kDa |
AA Sequence : | MPLCPLAHAMQPQSVLHSGYFHPLL RAWQTATTTLNASNLIYPIFVTDVP DDIQPITSLPGVARYGVKRLEEMLR PLVEEGLRCVLIFGVPSRVPKDERG SAADSEESPAIEAIHLLRKTFPNLL VACDVCLCPYTSHGHCGLLSENGAF RAEESRQRLAEVALAYAKAGCQVVA PSDMMDGRVEAIKEALMAHGLGNRV SVMSYSAKFASCFYGPFRDAAKSSP AFGDRRCYQLPPGARGLALRAVDRD VREGADMLMVKPGMPYLDIVREVKD KHPDLPLAVYHVSGEFAMLWHGAQA GAFDLKAAVLEAMTAFRRAGADIII TYYTPQLLQWLKEE |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ALAD aminolevulinate dehydratase [ Homo sapiens ] |
Official Symbol : | ALAD |
Synonyms : | ALAD; aminolevulinate dehydratase; aminolevulinate, delta , dehydratase; delta-aminolevulinic acid dehydratase; ALADH; PBGS; porphobilinogen synthase; aminolevulinate, delta-, dehydratase; MGC5057; |
Gene ID : | 210 |
mRNA Refseq : | NM_000031 |
Protein Refseq : | NP_000022 |
MIM : | 125270 |
UniProt ID : | P13716 |
Products Types
◆ Recombinant Protein | ||
Alad-513R | Recombinant Rat Alad Protein, His-tagged | +Inquiry |
Alad-1588M | Recombinant Mouse Alad Protein, Myc/DDK-tagged | +Inquiry |
ALAD-42C | Recombinant Cynomolgus Monkey ALAD Protein, His (Fc)-Avi-tagged | +Inquiry |
ALAD-446M | Recombinant Mouse ALAD Protein, His (Fc)-Avi-tagged | +Inquiry |
ALAD-512H | Recombinant Human ALAD Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ALAD-54HCL | Recombinant Human ALAD cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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