Recombinant Human ALPL Protein, MYC/DDK-tagged

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Recombinant Human ALPL Protein, MYC/DDK-tagged

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Cat.No. : ALPL-1994H
Product Overview : Recombinant human ALPL protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
Description : This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 55.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : ALPL alkaline phosphatase, liver/bone/kidney [ Homo sapiens ]
Official Symbol : ALPL
Synonyms : AP-TNAP; APTNAP; HOPS; TNAP; TNSALP
Gene ID : 249
mRNA Refseq : NM_000478
Protein Refseq : NP_000469
MIM : 171760
UniProt ID : P05186
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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