"ALPL" Related Products

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Recombinant Human ALPL Protein, MYC/DDK-tagged

Cat.No. : ALPL-1994H
Product Overview : Recombinant human ALPL protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
Description : This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 55.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : ALPL alkaline phosphatase, liver/bone/kidney [ Homo sapiens ]
Official Symbol : ALPL
Synonyms : AP-TNAP; APTNAP; HOPS; TNAP; TNSALP
Gene ID : 249
mRNA Refseq : NM_000478
Protein Refseq : NP_000469
MIM : 171760
UniProt ID : P05186

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