Recombinant Human ARHGAP24 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ARHGAP24-3271H
• Product Overview: ARHGAP24 MS Standard C13 and N15-labeled recombinant protein (NP_001020787) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 84.1 kDa
• AA Sequence: MEENNDSTENPQQGQGRQNAIKCGW LRKQGGFVKTWHTRWFVLKGDQLYY FKDEDETKPLGTIFLPGNKVSEHPC NEENPGKFLFEVVPGGDRDRMTANH ESYLLMASTQNDMEDWVKSIRRVIW GPFGGGIFGQKLEDTVRYEKRYGNR LAPMLVEQCVDFIRQRGLKEEGLFR LPGQANLVKELQDAFDCGEKPSFDS NTDVHTVASLLKLYLRELPEPVIPY AKYEDFLSCAKLLSKEEEAGVKELA KQVKSLPVVNYNLLKYICRFLDEVQ SYSGVNKMSVQNLATVFGPNILRPK VEDPLTIMEGTVVVQQLMSVMISKH DCLFPKDAELQSKPQDGVSNNNEIQ KKATMGQLQNKENNNTKDSPSRQCS WDKSESPQRSSMNNGSPTALSGSKT NSPKNSVHKLDVSRSPPLMVKKNPA FNKGSGIVTNGSFSSSNAEGLEKTQ TTPNGSLQARRSSSLKVSGTKMGTH SVQNGTVRMGILNSDTLGNPTNVRN MSWLPNGYVTLRDNKQKEQAGELGQ HNRLSTYDNVHQQFSMMNLDDKQSI DSATWSTSSCEISLPENSNSCRSST TTCPEQDFFGGNFEDPVLDGPPQDD LSHPRDYESKSDHRSVGGRSSRATS SSDNSETFVGNSSSNHSALHSLVSS LKQEMTKQKIEYESRIKSLEQRNLT LETEMMSLHDELDQERKKFTMIEIK MRNAERAKEDAEKRNDMLQKEMEQF FSTFGELTVEPRRTERGNTIWIQTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ARHGAP24 Rho GTPase activating protein 24 [ Homo sapiens (human) ]
• Official Symbol: ARHGAP24
• Synonyms: ARHGAP24; Rho GTPase activating protein 24; rho GTPase-activating protein 24; DKFZP564B1162; FilGAP; FLJ33877; rhoGAP of 73 kDa; sarcoma antigen NY-SAR-88; filamin-A-associated RhoGAP; rho-type GTPase-activating protein 24; RAC1- and CDC42-specific GTPase-activating protein of 72 kDa; p73; FILGAP; RCGAP72; RC-GAP72; p73RhoGAP; DKFZp564B1162
• Gene ID: 83478
• mRNA Refseq: NM_001025616
• Protein Refseq: NP_001020787
• MIM: 610586
• UniProt ID: Q8N264