Recombinant Human ATP7B Protein, Myc/ddk-tagged
Cat.No. : | ATP7B-468H |
Product Overview : | Recombinant protein of human ATPase, Cu++ transporting, beta polypeptide (ATP7B), transcript variant 1 with a C-Myc/DDK tag was expressed in HEK293T. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein is a monomer, and functions as a copper-transporting ATPase which exports copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease which is characterized by copper accumulation. |
Source : | HEK293T |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 157.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Gene Name : | ATP7B ATPase copper transporting beta [ Homo sapiens (human) ] |
Official Symbol : | ATP7B |
Synonyms : | ATP7B; ATPase copper transporting beta; WD; PWD; WC1; WND; copper-transporting ATPase 2; ATPase, Cu(2+)- transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide; Wilson disease-associated protein; copper pump 2; copper-transporting protein ATP7B; EC 7.2.2.8 |
Gene ID : | 540 |
mRNA Refseq : | NM_000053 |
Protein Refseq : | NP_000044 |
MIM : | 606882 |
UniProt ID : | P35670 |
Products Types
◆ Recombinant Protein | ||
Atp7b-275M | Recombinant Mouse Atp7b Protein, His-tagged | +Inquiry |
ATP7B-467H | Recombinant Human ATP7B Protein, His-tagged | +Inquiry |
Atp7b-676M | Recombinant Mouse Atp7b Protein, MYC/DDK-tagged | +Inquiry |
ATP7B-407H | Recombinant Human ATP7B Protein, His (Fc)-Avi-tagged | +Inquiry |
ATP7B-885M | Recombinant Mouse ATP7B Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ATP7B-8572HCL | Recombinant Human ATP7B 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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