Recombinant Human AXIN1 Protein
Cat.No. : | AXIN1-01H |
Product Overview : | Recombinant Human AXIN1 Protein was expressed in sf9 cell. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants. |
Source : | Sf9 cell |
Species : | Human |
Form : | Liquid |
Molecular Mass : | ~135 kDa |
Purity : | ≥75% |
Usage : | Research Use Only |
Storage : | Short Term Storage: -80°C. Long Term Storage: -80°C |
Concentration : | 0.05 µg/µl |
Storage Buffer : | Liquid. In 50mM TRIS-HCl, pH 7.5, containing 50mM NaCl, 10mM gluthathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Shipping : | Shipped with ice pack. |
Gene Name : | AXIN1 axin 1 [ Homo sapiens (human) ] |
Official Symbol : | AXIN1 |
Synonyms : | AXIN; PPP1R49 |
Gene ID : | 8312 |
mRNA Refseq : | NM_003502.4 |
Protein Refseq : | NP_003493.1 |
MIM : | 603816 |
UniProt ID : | O15169 |
Products Types
◆ Recombinant Protein | ||
AXIN1-565R | Recombinant Rat AXIN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
AXIN1-388H | Recombinant Human AXIN1 Protein, His-tagged | +Inquiry |
AXIN1-2524H | Recombinant Human AXIN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Axin1-684M | Recombinant Mouse Axin1 Protein, MYC/DDK-tagged | +Inquiry |
Axin1-389M | Recombinant Mouse Axin1 Protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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