Recombinant Human BGLAP Protein, MYC/DDK-tagged, C13 and N15-labeled

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Recombinant Human BGLAP Protein, MYC/DDK-tagged, C13 and N15-labeled

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Cat.No. : BGLAP-010H
Product Overview : BGLAP MS Standard C13 and N15-labeled recombinant protein (NP_954642) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 8.7 kDa
AA Sequence : MRALTLLALL ALAALCIAGQ AGAKPSGAES SKGAAFVSKQ EGSEVVKRPR RYLYQWLGAP VPYPDPLEPR REVCELNPDC DELADHIGFQ EAYRRFYGPV TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : BGLAP bone gamma-carboxyglutamate protein [ Homo sapiens (human) ]
Official Symbol : BGLAP
Synonyms : BGLAP; bone gamma-carboxyglutamate protein; BGP; OC; OCN; osteocalcin; bone gamma-carboxyglutamate (gla) protein (osteocalcin); gamma-carboxyglutamic acid-containing protein
Gene ID : 632
mRNA Refseq : NM_199173
Protein Refseq : NP_954642
MIM : 112260
UniProt ID : P02818
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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