Recombinant Human BIRC3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: BIRC3-2910H
• Product Overview: BIRC3 MS Standard C13 and N15-labeled recombinant protein (NP_001156) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 68.4 kDa
• AA Sequence: MNIVENSIFLSNLMKSANTFELKYD LSCELYRMSTYSTFPAGVPVSERSL ARAGFYYTGVNDKVKCFCCGLMLDN WKRGDSPTEKHKKLYPSCRFVQSLN SVNNLEATSQPTFPSSVTNSTHSLL PGTENSGYFRGSYSNSPSNPVNSRA NQDFSALMRSSYHCAMNNENARLLT FQTWPLTFLSPTDLAKAGFYYIGPG DRVACFACGGKLSNWEPKDNAMSEH LRHFPKCPFIENQLQDTSRYTVSNL SMQTHAARFKTFFNWPSSVLVNPEQ LASAGFYYVGNSDDVKCFCCDGGLR CWESGDDPWVQHAKWFPRCEYLIRI KGQEFIRQVQASYPHLLEQLLSTSD SPGDENAESSIIHFEPGEDHSEDAI MMNTPVINAAVEMGFSRSLVKQTVQ RKILATGENYRLVNDLVLDLLNAED EIREEERERATEEKESNDLLLIRKN RMALFQHLTCVIPILDSLLTAGIIN EQEHDVIKQKTQTSLQARELIDTIL VKGNIAATVFRNSLQEAEAVLYEHL FVQQDIKYIPTEDVSDLPVEEQLRR LQEERTCKVCMDKEVSIVFIPCGHL VVCKDCAPSLRKCPICRSTIKGTVR TFLSTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: BIRC3 baculoviral IAP repeat containing 3 [ Homo sapiens (human) ]
• Official Symbol: BIRC3
• Synonyms: BIRC3; baculoviral IAP repeat containing 3; API2, baculoviral IAP repeat containing 3; baculoviral IAP repeat-containing protein 3; apoptosis inhibitor 2; c IAP2; cIAP2; hiap 1; inhibitor of apoptosis protein 1; MALT2; mammalian IAP homolog C; MIHC; RNF49; TNFR2 TRAF signaling complex protein; IAP-1; IAP homolog C; RING finger protein 49; baculoviral IAP repeat-containing 3; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1; AIP1; API2; CIAP2; HAIP1; HIAP1; c-IAP2
• Gene ID: 330
• mRNA Refseq: NM_001165
• Protein Refseq: NP_001156
• MIM: 601721
• UniProt ID: Q13489