Recombinant Human C3 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human C3 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : C3-3052H
Product Overview : C3 MS Standard C13 and N15-labeled recombinant protein (NP_000055) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 187 kDa
AA Sequence : MGPTSGPSLL LLLLTHLPLA LGSPMYSIIT PNILRLESEE TMVLEAHDAQ GDVPVTVTVH DFPGKKLVLS SEKTVLTPAT NHMGNVTFTI PANREFKSEK GRNKFVTVQA TFGTQVVEKV VLVSLQSGYL FIQTDKTIYT PGSTVLYRIF TVNHKLLPVG RTVMVNIENP EGIPVKQDSL SSQNQLGVLP LSWDIPELVN MGQWKIRAYY ENSPQQVFST EFEVKEYVLP SFEVIVEPTE KFYYIYNEKG LEVTITARFL YGKKVEGTAF VIFGIQDGEQ RISLPESLKR IPIEDGSGEV VLSRKVLLDG VQNLRAEDLV GKSLYVSATV ILHSGSDMVQ AERSGIPIVT SPYQIHFTKT PKYFKPGMPF DLMVFVTNPD GSPAYRVPVA VQGEDTVQSL TQGDGVAKLS INTHPSQKPL SITVRTKKQE LSEAEQATRT MQALPYSTVG NSNNYLHLSV LRTELRPGET LNVNFLLRMD RAHEAKIRYY TYLIMNKGRL LKAGRQVREP GQDLVVLPLS ITTDFIPSFR LVAYYTLIGA SGQREVVADS VWVDVKDSCV GSLVVKSGQS EDRQPVPGQQ MTLKIEGDHG ARVVLVAVDK GVFVLNKKNK LTQSKIWDVV EKADIGCTPG SGKDYAGVFS DAGLTFTSSS GQQTAQRAEL QCPQPAARRR RSVQLTEKRM DKVGKYPKEL RKCCEDGMRE NPMRFSCQRR TRFISLGEAC KKVFLDCCNY ITELRRQHAR ASHLGLARSN LDEDIIAEEN IVSRSEFPES WLWNVEDLKE PPKNGISTKL MNIFLKDSIT TWEILAVSMS DKKGICVADP FEVTVMQDFF IDLRLPYSVV RNEQVEIRAV LYNYRQNQEL KVRVELLHNP AFCSLATTKR RHQQTVTIPP KSSLSVPYVI VPLKTGLQEV EVKAAVYHHF ISDGVRKSLK VVPEGIRMNK TVAVRTLDPE RLGREGVQKE DIPPADLSDQ VPDTESETRI LLQGTPVAQM TEDAVDAERL KHLIVTPSGC GEQNMIGMTP TVIAVHYLDE TEQWEKFGLE KRQGALELIK KGYTQQLAFR QPSSAFAAFV KRAPSTWLTA YVVKVFSLAV NLIAIDSQVL CGAVKWLILE KQKPDGVFQE DAPVIHQEMI GGLRNNNEKD MALTAFVLIS LQEAKDICEE QVNSLPGSIT KAGDFLEANY MNLQRSYTVA IAGYALAQMG RLKGPLLNKF LTTAKDKNRW EDPGKQLYNV EATSYALLAL LQLKDFDFVP PVVRWLNEQR YYGGGYGSTQ ATFMVFQALA QYQKDAPDHQ ELNLDVSLQL PSRSSKITHR IHWESASLLR SEETKENEGF TVTAEGKGQG TLSVVTMYHA KAKDQLTCNK FDLKVTIKPA PETEKRPQDA KNTMILEICT RYRGDQDATM SILDISMMTG FAPDTDDLKQ LANGVDRYIS KYELDKAFSD RNTLIIYLDK VSHSEDDCLA FKVHQYFNVE LIQPGAVKVY AYYNLEESCT RFYHPEKEDG KLNKLCRDEL CRCAEENCFI QKSDDKVTLE ERLDKACEPG VDYVYKTRLV KVQLSNDFDE YIMAIEQTIK SGSDEVQVGQ QRTFISPIKC REALKLEEKK HYLMWGLSSD FWGEKPNLSY IIGKDTWVEH WPEEDECQDE ENQKQCQDLG AFTESMVVFG CPNTRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : C3 complement component 3 [ Homo sapiens (human) ]
Official Symbol : C3
Synonyms : C3; complement component 3; complement C3; CPAMD1; complement component C3; acylation-stimulating protein cleavage product; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; ASP; AHUS5; ARMD9;
Gene ID : 718
mRNA Refseq : NM_000064
Protein Refseq : NP_000055
MIM : 120700
UniProt ID : P01024

Products Types

◆ Recombinant Protein

C3-732MRecombinant Mouse C3 Protein, MYC/DDK-tagged+Inquiry
C3-7632MRecombinant Mouse C3 protein, His-tagged+Inquiry
C3-4324RRecombinant Rabbit C3 Protein+Inquiry
C3-1841HRecombinant Human C3 Protein, MYC/DDK-tagged+Inquiry
C3-1149HRecombinant Human C3 Protein, His-tagged+Inquiry

See All C3 Recombinant Protein

◆ Native Protein

C3-8092HNative Human Plasma COMPLEMENT C (C3)+Inquiry
C3-147CNative Botulinum C3 Enzyme+Inquiry
C3-194HNative Human Complement C3c+Inquiry

See All C3 Native Protein

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albicansC15orf55C8orf86C1orf229C20orf78C17orf105C17orf108C9orf172C1orf228C10orf107C14orf2C14orf166BC19orf44C19orf57C19orf59C19orf60C19orf66C19orf70C20orf26C10orf111C10orf113C10orf118C10orf12C10orf120C10orf128C10orf32C10orf35C10orf53C10orf55C10orf68C10orf71C10orf90C10orf91C11orf1C11orf10C11orf34C11orf45C11orf48C11orf49C11orf52C11orf70C11orf80C11orf84C11orf86C11orf9C12orf23C12orf39C12orf43C12orf45C12orf52C12orf60C12orf70C12orf71C12orf73C14orf101C14orf43C14orf45C14orf93C15orf23C15orf43C15orf53C15orf57C15orf59C16orf79C16orf80C16orf88C17orf47C17orf58C17orf67C17orf99C18orf26C18orf32C18orf62C19orf26C19orf42C1orf105C1orf106C1orf109C1orf112C1orf114C1orf123C1orf158C1orf162C1orf168C1orf173C1orf174C1orf192C1orf194C1orf198C1orf21C1orf27C1orf61C1orf64C1orf68C1orf85C1orf86C20orf151C20orf152C20orf166C22orf15C22orf23C22orf28C22orf29C22orf32C2CD3C2orf44C2orf65C2orf66C2orf72C2orf76C2orf83C3orf20C3orf26C4orf21C4orf3C4orf40C5orf15C5orf22C5orf34C5orf44C5orf48C6orf106C6orf130C6orf132C6orf15C6orf162C6orf163C6orf165C6orf195C6orf222C6orf225C6orf57C6orf89C8orf58C8orf74C9orf11C9orf116C9orf131C9orf135C9orf139C7orf25C7orf34C7orf41C7orf45C7orf53C7orf57C7orf59C7orf60C8orf40C8orf4C8orf42C8orf44C8orf47C9orf16C9orf163C9orf169C9orf37C9orf57C9orf50C9orf66C9orf84C9orf91C19ORF76C8orf85C15ORF38-AP3S2C1orf115C1ORF233C10orf11C11orf20C11orf35C11orf40C11orf83C11orf88C11ORF93C11ORF94C11ORF95C13orf35C14orf178C16orf55C17orf100C17orf102C17ORF107C17orf79C17orf96C19orf69C2orf27BC2orf48C2orf88C2ORF91C22orf24C22orf26C4orf17C5ORF63C6ORF228C6orf47C6orf52C7orf26C8orf37C8orf82C8ORF87C1QL4C19orf63C87977C030019I05RikC530028O21RikC330019G07RikC5ORF65C030006K11RikC030030A07RikC030039L03RikC030046E11RikC030046I01RikC030048B08RikC330005M16RikC330006K01RikC330007P06RikC330018D20RikC330021F23RikC330027C09RikC530008M17RikC630004H02RikC5ORF62C17ORF109C17ORF110C15orf42C3orf71C1QTNF9BC2cd4aC2cd4dC1orf101C1orf146C1orf185C1orf189C1orf204C1orf210C1orf212C1orf226C1orf227C1H6orf35C10orf105C10orf131C10orf76C11orf31C11orf91C11orf96C12orf44C12orf56C12orf57C12orf76C14orf142C14orf182C14orf79C15orf56C15orf60C15orf61C16orf3C16orf52C16orf59C16orf82C16orf86C16orf89C16orf90C16orf91C16orf92C16orf93C16orf95C17orf72C17orf89C18orf42C18orf63C19orf48C19orf71C19orf77C2orf15C2orf49C2orf54C2orf61C2orf70C2orf73C2orf74C2orf78C2orf81C2orf82C20orf118C20orf85C22orf46C3orf14C3orf22C3orf35C3orf43C3orf45C3orf79C3orf80C4orf29C4orf34C4orf48C4orf51C4orf52C5orf30C5orf38C5orf42C5orf45C5orf47C5orf52C5orf58C6orf136C6orf141C6orf170C6orf203C6orf211C6orf226C6orf48C6orf99C7orf33C7orf63C7orf65C7orf66C7orf71C7orf73C8orf46C8orf73C9orf129C9orf142C9orf171C9orf24C9orf47C9orf85C130022K22RikC3orf19C14orf38C1raC4bpC77080C77370C78339C80913C86695C87414C87436C130026I21RikC130039O16RikC130050O18RikC130060K24RikC130074G19RikC130079G13RikC230052I12RikC230081A13RikC20orf94C3orf78C3orf77C14orf176C16orf7C2orf39C11orf42C12orf65C15orf48C19orf80C11H2orf49

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