Recombinant Human C5 Protein, GST-Tagged

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Recombinant Human C5 Protein, GST-Tagged

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Cat.No. : C5-0077H
Product Overview : Human C5 partial ORF (NP_001726, 1550 a.a. - 1661 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 38.06 kDa
AA Sequence : QTACKPEIAY AYKVSITSIT VENVFVKYKA TLLDIYKTGE AVAEKDSEIT FIKKVTCTNA ELVKGRQYLI MGKEALQIKY NFSFRYIYPL DSLTWIEYWP RDTTCSSCQA FL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : C5 complement component 5 [ Homo sapiens ]
Official Symbol : C5
Synonyms : C5; complement component 5; complement C5; CPAMD4; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; FLJ17816; FLJ17822; MGC142298;
Gene ID : 727
mRNA Refseq : NM_001735
Protein Refseq : NP_001726
MIM : 120900
UniProt ID : P01031

Products Types

◆ Recombinant Protein

C5-575HRecombinant Human C5 Protein (Gln19-Cys1676), His-FLAG-tagged+Inquiry
C5-562HRecombinant Human C5 Protein, GST-tagged+Inquiry
C5-511RRecombinant Rat C5 protein, His-tagged+Inquiry
C5-851HRecombinant Human C5 protein (W917S), His-tagged+Inquiry
C5-26131THRecombinant Human C5, His-tagged+Inquiry

See All C5 Recombinant Protein

◆ Native Protein

C5-53HNative Human Complement C5+Inquiry
C5-10540HNative Human C5+Inquiry

See All C5 Native Protein

◆ Lysates

C5-8020HCLRecombinant Human C5 293 Cell Lysate+Inquiry

See All C5 Lysates

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