Recombinant Human CD59 protein, T7/His-tagged
Cat.No. : | CD59-76H |
Product Overview : | Recombinant human CD59 extracellular domain cDNA (26 - 102 aa) fused with T7-His-TEV cleavage site Tag (29aa) at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Human |
Tag : | T7/His |
Form : | 0.50 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol. |
AA Sequence : | MASMTGGQQMGRGHHHHHHGNLYFQ GGEFALVQCYNCPNPTADCKTAVNC SSDFDACLITKAGLQVYNKCWKFEH CNFNDVTTRLRENELTYYCCRKDLC NFNEQLEN |
Purity : | >90% by SDS-PAGE |
Applications : | 1. Protein can be used as coating matrix protein for CD59 mediated cell functions and differentiation regulation study in vitro.2. As potential disease diagnosis biomarker protein for breast cancer or systemic lupus.3. As antigen for specific antibody production. |
Storage : | Keep at -80centigrade for long term storage. Product is stable at 4 centigrade for at least 30 days. |
Gene Name : | CD59 CD59 molecule, complement regulatory protein [ Homo sapiens ] |
Official Symbol : | CD59 |
Synonyms : | CD59; CD59 molecule, complement regulatory protein; CD59 antigen p18 20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344) , CD59 antigen, complement regulatory protein , MIC11, MIN1, MIN2, MIN3, MSK21; CD59 glycoprotein; 16. |
Gene ID : | 966 |
mRNA Refseq : | NM_000611 |
Protein Refseq : | NP_000602 |
MIM : | 107271 |
UniProt ID : | P13987 |
Chromosome Location : | 11p13 |
Pathway : | Arf6 trafficking events, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; |
Function : | protein binding; |
Products Types
◆ Recombinant Protein | ||
CD59-692H | Recombinant Human CD59 Protein, His and C-hFc-tagged | +Inquiry |
CD59-572R | Recombinant Rhesus Macaque CD59 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD59-3116H | Recombinant Human CD59 Protein, MYC/DDK-tagged | +Inquiry |
CD59-543H | Recombinant Human CD59 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD59-693H | Recombinant Human CD59 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CD59-1365RCL | Recombinant Rat CD59 cell lysate | +Inquiry |
CD59-1968HCL | Recombinant Human CD59 cell lysate | +Inquiry |
CD59-1019CCL | Recombinant Cynomolgus CD59 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionIn hemolytic diseases, the deficiency or dysfunction of CD59 may lead to excessive lysis of red blood cells because the formation of the complement C5b-9 complex cannot be effectively prevented.
Yes, the expression level of CD59 can vary in different cell types. In general, it is expressed higher in blood cells and some tumor cells.
When researching CD59, laboratories may encounter technical challenges such as selecting the appropriate assay, ensuring the quality and consistency of samples, and the complexity of interpreting results. In addition, CD59 expression variations in different cell types and experimental conditions need to be considered.
Aberrant expression of CD59 has been associated with a variety of diseases, including but not limited to hemolytic diseases, certain types of cancer, and autoimmune diseases.
CD59 expression can be detected using flow cytometry, immunofluorescence staining, or western blotting.
The current treatment for CD59 is still in the research stage, and there is no drug approved for clinical use. However, some studies are exploring the use of gene therapy or antibody therapy to modulate CD59 expression or function.
Customer Reviews (3)
Write a reviewThe quality is very high and the reliability is very helpful for our research results.
There are no doping impurities, the experimental effect is very good, and I will recommend it to other students.
Easy to operate and cost-effective.
Ask a Question for All CD59 Products
Required fields are marked with *
My Review for All CD59 Products
Required fields are marked with *
Inquiry Basket