Recombinant Human CFD protein, Fc-tagged
Cat.No. : | CFD-3810H |
Product Overview : | Recombinant Human CFD (Ile26-Ala253) protein was fused to human IgG1 Fc tag at C-terminus and expressed in human 293 cells (HEK293). |
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Description : | Complement factor D (CFD) is also known as Adipsin, C3 convertase activator, Properdin factor D (PFD), which contains one peptidase S1 domain and belongs to the peptidase S1 family. CFD/Adipsin cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. CFD/Adipsin is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD/Adipsin are the cause of complement factor D deficiency which predisposes to invasive meningococcal disease. |
Source : | HEK293 |
Species : | Human |
Tag : | human IgG1 Fc |
Predicted N Terminal : | Ile26 |
Form : | Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 50.8 kDa. The protein migrates as 53 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Ile26-Ala253 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | CFD |
Official Symbol : | CFD |
Synonyms : | CFD; complement factor D (adipsin); D component of complement (adipsin), DF, PFD, properdin factor D; complement factor D; ADN; properdin factor D; C3 convertase activator; complement factor D preproprotein; D component of complement (adipsin); DF; PFD; ADIPSIN |
Gene ID : | 1675 |
mRNA Refseq : | NM_001928 |
Protein Refseq : | NP_001919 |
MIM : | 134350 |
UniProt ID : | P00746 |
Products Types
◆ Recombinant Protein | ||
Cfd-546M | Recombinant Mouse Cfd Protein, MYC/DDK-tagged | +Inquiry |
CFD-2178R | Recombinant Rat CFD Protein (26-263 aa), His-tagged | +Inquiry |
CFD-790H | Recombinant Human CFD Protein | +Inquiry |
CFD-2662H | Recombinant Human CFD Protein, His (Fc)-Avi-tagged | +Inquiry |
CFD-760H | Recombinant Human CFD Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
CFD-348H | Active Native Human Factor D | +Inquiry |
◆ Lysates | ||
CFD-1864HCL | Recombinant Human CFD cell lysate | +Inquiry |
CFD-1870MCL | Recombinant Mouse CFD cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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