"CHUK" Related Products

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Recombinant Human CHUK protein, Flag-tagged, Biotinylated

Cat.No.: CHUK-52H
Product Overview: Recombinant Human IKKα [1-745(end) amino acids of accession number NP_001269.3] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.
Source: Insect cell
Species: Human
Tag: Flag
Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
Molecular Mass: 88 kDa
Purity: >85% as determined by SDS-PAGE and CBB staining
Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name: CHUK conserved helix-loop-helix ubiquitous kinase [ Homo sapiens ]
Official Symbol: CHUK
Synonyms: CHUK; TCF16; IkBKA; IKK alpha; IKK1; IKKA; NFKBIKA; TCF-16; IKK-a kinase; I-kappa-B kinase 1; IKBKA; IKK-alpha;
Gene ID: 1147
mRNA Refseq: NM_001278
Protein Refseq: NP_001269
MIM: 600664
UniProt ID: O15111
Chromosome Location: 10q24-q25
Pathway: AKT phosphorylates targets in the cytosol, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem;
Function: ATP binding; IkappaB kinase activity; nucleotide binding; protein binding; protein kinase activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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