Recombinant Human CXCL1, His-tagged
| Cat.No. : | CXCL1-11715H |
| Product Overview : | Recombinant Human CXCL1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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| Description : | This gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. |
| Source : | E.coli |
| Species : | Human |
| Tag : | His |
| Protein length : | 1-107a.a. |
| Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
| Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
| Gene Name : | CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) [ Homo sapiens ] |
| Official Symbol : | CXCL1 |
| Synonyms : | CXCL1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); fibroblast secretory protein , FSP, GRO1, GRO1 oncogene (melanoma growth stimulating activity, alpha) , MGSA; growth-regulated alpha protein; GROa; MGSA a; NAP 3; SCYB1; MGSA alpha; GRO-alpha(1-73); C-X-C motif chemokine 1; fibroblast secretory protein; neutrophil-activating protein 3; melanoma growth stimulatory activity alpha; GRO1 oncogene (melanoma growth-stimulating activity); GRO1 oncogene (melanoma growth stimulating activity, alpha); FSP; GRO1; MGSA; NAP-3; MGSA-a; |
| Gene ID : | 2919 |
| mRNA Refseq : | NM_001511 |
| Protein Refseq : | NP_001502 |
| MIM : | 155730 |
| UniProt ID : | P09341 |
| Chromosome Location : | 4q13.3 |
| Pathway : | Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; |
| Function : | chemokine activity; enzyme activator activity; growth factor activity; receptor binding; |
Products Types
| ◆ Recombinant Protein | ||
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| Cxcl1-068M | Active Recombinant Mouse Cxcl1 Protein | +Inquiry |
| CXCL1-134H | Active Recombinant Human CXCL1 Protein (Ala35-Asn107), N-His tagged, Animal-free, Carrier-free | +Inquiry |
| CXCL1-272C | Active Recombinant Human CXCL1 Protein | +Inquiry |
| CXCL1-982H | Recombinant Human CXCL1 Protein, His-SUMO-tagged | +Inquiry |
| ◆ Native Protein | ||
| CXCL1-27707TH | Native Human CXCL1 | +Inquiry |
| ◆ Lysates | ||
| CXCL1-425HCL | Recombinant Human CXCL1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionTherapeutic strategies targeting CXCL1 aim to modulate its activity in diseases like cancer and chronic inflammation.
It mediates inflammation by promoting leukocyte migration and activation.
In cancer, CXCL1 can promote tumor growth, metastasis, and angiogenesis.
CXCL1 contributes to angiogenesis, supporting new blood vessel formation.
CXCL1 is a chemokine that attracts neutrophils to sites of infection or injury.
CXCL1 levels are elevated in conditions like cancer, inflammatory diseases, and infections.
CXCL1 expression is regulated by various stimuli, including cytokines and growth factors.
Customer Reviews (3)
Write a reviewEfficient delivery, great service. -
Product as described, perfect. -
Reliable for protein work. -
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