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Active Recombinant Human Chemokine (C-X-C Motif) Ligand 1, MIgG2a Fc-tagged
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Cat.No. : | CXCL1-222H Optional Service: Optional requirements on this protein |
Product Overview : | The extracellular domain of human CXCL1 (AAH11976.1)(Ala35-Asn107) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell. |
Description : | This gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4 |
Source : | CHO cell |
Species : | Human |
Tag : | MIgG2a Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to induce myeloperoxidase. |
Molecular Mass : | 34KDa (monomer) |
AA Sequence : | Ala35-Asn107 |
Endotoxin : | <0.06 eu/μg as determined by lal>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) [ Homo sapiens ] |
Official Symbol : | CXCL1 |
Synonyms : | CXCL1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); fibroblast secretory protein , FSP, GRO1, GRO1 oncogene (melanoma growth stimulating activity, alpha) , MGSA; growth-regulated alpha protein; GROa; MGSA a; NAP 3; SCYB1; MGSA alpha; GRO-alpha(1-73); C-X-C motif chemokine 1; fibroblast secretory protein; neutrophil-activating protein 3; melanoma growth stimulatory activity alpha; GRO1 oncogene (melanoma growth-stimulating activity); GRO1 oncogene (melanoma growth stimulating activity, alpha); FSP; GRO1; MGSA; NAP-3; MGSA-a; |
Gene ID : | 2919 |
mRNA Refseq : | NM_001511 |
Protein Refseq : | NP_001502 |
MIM : | 155730 |
UniProt ID : | P09341 |
Chromosome Location : | 4q13.3 |
Pathway : | Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; |
Function : | chemokine activity; enzyme activator activity; growth factor activity; receptor binding; |
◆ Recombinant Protein
Cxcl1-068M | Recombinant Mouse Cxcl1 Protein | +Inquiry |
CXCL1-2155H | Recombinant Human CXCL1 Protein, GST-tagged | +Inquiry |
CXCL1-982H | Recombinant Human CXCL1 Protein, His-SUMO-tagged | +Inquiry |
CXCL1-001H | Recombinant Human CXCL1 Protein, MBP-tagged | +Inquiry |
Cxcl1-069M | Recombinant Mouse Cxcl1 Protein | +Inquiry |
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◆ Native Protein
CXCL1-27707TH | Native Human CXCL1 | +Inquiry |
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◆ Lysates
CXCL1-425HCL | Recombinant Human CXCL1 cell lysate | +Inquiry |
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CXCL1Cxcl10CXCL11CXCL12CXCL13CXCL14Cxcl15Cxcl16Cxcl2CXCL3Cxcl5CXCL6CXCL9Cxcl17CXCL7
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