Recombinant Human DNM1L Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | DNM1L-2471H |
| Product Overview : | DNM1L MS Standard C13 and N15-labeled recombinant protein (NP_036193) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 79.4 kDa |
| AA Sequence : | MEALIPVINK LQDVFNTVGA DIIQLPQIVV VGTQSSGKSS VLESLVGRDL LPRGTGIVTR RPLILQLVHV SQEDKRKTTG EENGVEAEEW GKFLHTKNKL YTDFDEIRQE IENETERISG NNKGVSPEPI HLKIFSPNVV NLTLVDLPGM TKVPVGDQPK DIELQIRELI LRFISNPNSI ILAVTAANTD MATSEALKIS REVDPDGRRT LAVITKLDLM DAGTDAMDVL MGRVIPVKLG IIGVVNRSQL DINNKKSVTD SIRDEYAFLQ KKYPSLANRN GTKYLARTLN RLLMHHIRDC LPELKTRINV LAAQYQSLLN SYGEPVDDKS ATLLQLITKF ATEYCNTIEG TAKYIETSEL CGGARICYIF HETFGRTLES VDPLGGLNTI DILTAIRNAT GPRPALFVPE VSFELLVKRQ IKRLEEPSLR CVELVHEEMQ RIIQHCSNYS TQELLRFPKL HDAIVEVVTC LLRKRLPVTN EMVHNLVAIE LAYINTKHPD FADACGLMNN NIEEQRRNRL ARELPSAVSR DKLIQDSRRE TKNVASGGGG VGDGVQEPTT GNWRGMLKTS KAEELLAEEK SKPIPIMPAS PQKGHAVNLL DVPVPVARKL SAREQRDCEV IERLIKSYFL IVRKNIQDSV PKAVMHFLVN HVKDTLQSEL VGQLYKSSLL DDLLTESEDM AQRRKEAADM LKALQGASQI IAEIRETHLW TRTRPLEQKL ISEEDLAAND ILDYKDDDDK V |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | DNM1L dynamin 1-like [ Homo sapiens (human) ] |
| Official Symbol : | DNM1L |
| Synonyms : | DNM1L; dynamin 1-like; dynamin-1-like protein; DRP1; DVLP; DYMPLE; HDYNIV; VPS1; dynamin-like protein 4; dynamin-like protein IV; Dnm1p/Vps1p-like protein; dynamin-related protein 1; dynamin family member proline-rich carboxyl-terminal domain less; DLP1; EMPF; DYNIV-11; FLJ41912; |
| Gene ID : | 10059 |
| mRNA Refseq : | NM_012063 |
| Protein Refseq : | NP_036193 |
| MIM : | 603850 |
| UniProt ID : | O00429 |
◆ Recombinant Protein
| Dnm1l-2618M | Recombinant Mouse Dnm1l Protein, Myc/DDK-tagged | +Inquiry |
| DNM1L-2584H | Recombinant Human DNM1L Protein (1-710 aa), His-Myc-tagged | +Inquiry |
| DNM1L-2785H | Recombinant Human DNM1L Protein, GST-tagged | +Inquiry |
| DNM1L-4736M | Recombinant Mouse DNM1L Protein | +Inquiry |
| DNM1L-3555C | Recombinant Chicken DNM1L | +Inquiry |
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◆ Lysates
| DNM1L-6859HCL | Recombinant Human DNM1L 293 Cell Lysate | +Inquiry |
| DNM1L-6858HCL | Recombinant Human DNM1L 293 Cell Lysate | +Inquiry |
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