Recombinant Human DSP Protein, His-tagged

• Cat.No.: DSP-401H
• Product Overview: Recombinant Human DSP(Phe2609~Ala2822) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Phe2609~Ala2822
• Description: This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 27.0kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: DSP desmoplakin [ Homo sapiens ]
• Official Symbol: DSP
• Synonyms: DSP; desmoplakin; desmoplakin (DPI, DPII); DPI; DPII; KPPS2; PPKS2; desmoplakin I; desmoplakin II; 250/210 kDa paraneoplastic pemphigus antigen; DP
• Gene ID: 1832
• mRNA Refseq: NM_001008844
• Protein Refseq: NP_001008844
• MIM: 125647
• UniProt ID: P15924