Recombinant Human DSP Protein (78-300 aa), His-tagged

• Cat.No.: DSP-1381H
• Product Overview: Recombinant Human DSP Protein (78-300 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Partial.

Specification

• Description: Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.
• Source: Yeast
• Species: Human
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 28.1 kDa
• Protein length: 78-300 aa
• AA Sequence: CSDCLMRAELIVQPELKYGDGIQLT RSRELDECFAQANDQMEILDSLIRE MRQMGQPCDAYQKRLLQLQEQMRAL YKAISVPRVRRASSKGGGGYTCQSG SGWDEFTKHVTSECLGWMRQQRAEM DMVAWGVDLASVEQHINSHRGIHNS IGDYRWQLDKIKADLREKSAIYQLE EEYENLLKASFERMDHLRQLQNIIQ ATSREIMWINDCEEEELLYDWSD
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: DSP desmoplakin [ Homo sapiens ]
• Official Symbol: DSP
• Synonyms: DSP; desmoplakin; DPI; DPII; KPPS2; PPKS2; desmoplakin I; DP
• Gene ID: 1832
• mRNA Refseq: NM_001008844
• Protein Refseq: NP_001008844
• MIM: 125647
• UniProt ID: P15924