Recombinant Human FGF12 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: FGF12-290H
• Product Overview: FGF12 MS Standard C13 and N15-labeled recombinant protein (NP_066360) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. [provided by RefSeq, Dec 2019]
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 27.2 kDa
• AA Sequence: MAAAIASSLIRQKRQARESNSDRVS ASKRRSSPSKDGRSLCERHVLGVFS KVRFCSGRKRPVRRRPEPQLKGIVT RLFSQQGYFLQMHPDGTIDGTKDEN SDYTLFNLIPVGLRVVAIQGVKASL YVAMNGEGYLYSSDVFTPECKFKES VFENYYVIYSSTLYRQQESGRAWFL GLNKEGQIMKGNRVKKTKPSSHFVP KPIEVCMYREPSLHEIGEKQGRSRK SSGTPTMNGGKVVNQDSTTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FGF12 fibroblast growth factor 12 [ Homo sapiens (human) ]
• Official Symbol: FGF12
• Synonyms: FGF12; fibroblast growth factor 12; FGF12B; FHF1; fibroblast growth factor 12B; fibroblast growth factor FGF 12b; fibroblast growth factor homologous factor 1; myocyte activating factor; FHF-1; FGF-12; myocyte-activating factor; fibroblast growth factor FGF-12b
• Gene ID: 2257
• mRNA Refseq: NM_021032
• Protein Refseq: NP_066360
• MIM: 601513
• UniProt ID: P61328