Recombinant Human IGF1R Protein, MYC/DDK-tagged

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Recombinant Human IGF1R Protein, MYC/DDK-tagged

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Cat.No. : IGF1R-1392H
Product Overview : Recombinant human IGF1R protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 81 kDa
Purity : >50 ug/mL as determined by microplate BCA method
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : IGF1R insulin-like growth factor 1 receptor [ Homo sapiens ]
Official Symbol : IGF1R
Synonyms : CD221; IGFIR; IGFR; JTK13
Gene ID : 3480
mRNA Refseq : NM_000875
Protein Refseq : NP_000866
MIM : 147370
UniProt ID : P08069

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