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Recombinant Human IL11RA Protien, GST-tagged

Cat.No. : IL11RA-561H
Product Overview : Recombinant Human IL11RA Protien(NP_001136256)(184-361 aa), fused to GST tag, was expressed in E. coli.
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Source : E. coli
Species : Human
Tag : GST
Form : The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.). 5 % trehalose and 5 % mannitol are added as protectants before lyophilization.
Protein length : 184-361 aa
AA Sequence : GAEFWSQYRINVTEVNPLGASTRLL DVSLQSILRPDPPQGLRVESVPGYP RRLRASWTYPASWPCQPHFLLKFRL QYRPAQHPAWSTVEPAGLEEVITDA VAGLPHAVRVSARDFLDAGTWSTWS PEAWGTPSTGTIPKEIPAWGQLHTQ PEVEPQVDSPAPPRPSLQPHPRLLD HRD
Purity : 90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
Storage : Short-term storage: Store at 2-8°C for (1-2 weeks).
Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
Reconstitution : Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage (see Stability and Storage for more details).
If a different concentration is needed for your purposes please adjust the reconstitution volume as required (please note: the ion concentration of the final solution will vary according to the volume used).
Note: Centrifuge vial before opening. When reconstituting, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution.
Gene Name : IL11RA interleukin 11 receptor, alpha [ Homo sapiens ]
Official Symbol : IL11RA
Synonyms : IL11RA; interleukin 11 receptor, alpha; interleukin-11 receptor subunit alpha; IL-11RA; IL-11R subunit alpha; IL-11 receptor subunit alpha; interleukin-11 receptor alpha chain; CRSDA; MGC2146;
Gene ID : 3590
mRNA Refseq : NM_001142784
Protein Refseq : NP_001136256
MIM : 600939
UniProt ID : Q14626

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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Can you explain how phosphoproteomics and mass spectrometry shed light on IL11RA-mediated signaling cascades and post-translational modifications? 04/16/2022

Phosphoproteomics and mass spectrometry reveal IL11RA-related signaling pathways.

How are flow cytometry and fluorescence-activated cell sorting (FACS) employed to analyze IL11RA expression on different cell populations? 07/13/2021

Flow cytometry and FACS analyze IL11RA expression on different cell types.

Could you elaborate on how X-ray crystallography and cryo-electron microscopy contribute to understanding the three-dimensional structure of IL11RA? 06/12/2020

X-ray crystallography and cryo-EM reveal the three-dimensional structure of IL11RA.

What insights have gene expression profiling and RNA sequencing provided regarding IL11RA-related molecular pathways and networks? 09/10/2019

Gene expression profiling and RNA sequencing unveil IL11RA-associated molecular networks.

How do techniques like co-immunoprecipitation and pull-down assays validate IL11RA's interactions with IL11 and other signaling partners? 08/29/2019

Co-immunoprecipitation and pull-down assays confirm IL11RA interactions with IL11 and other partners.

What role does site-directed mutagenesis play in identifying IL11RA residues critical for IL11 binding and downstream signaling activation? 07/28/2019

Site-directed mutagenesis identifies IL11RA residues crucial for binding and signaling.

How are animal models like transgenic mice and tissue-specific knockouts utilized to study the in vivo roles of IL11RA in development and disease? 05/18/2019

Transgenic mice and knockouts study IL11RA's roles in development and disease.

Can you explain the experimental strategies used to characterize IL11RA isoforms and their differential roles in IL11 signaling? 04/08/2018

Experimental strategies characterize IL11RA isoforms and their distinct roles in IL11 signaling.

How are biophysical techniques such as isothermal titration calorimetry and surface plasmon resonance used to determine IL11RA's binding affinities and kinetics? 03/08/2018

Isothermal titration calorimetry and surface plasmon resonance measure IL11RA binding properties.

What methods like CRISPR-Cas9 knockout and RNA interference help elucidate the functional significance of IL11RA in specific biological contexts? 10/18/2017

CRISPR-Cas9 knockout and RNA interference reveal IL11RA's functions in specific contexts.

Customer Reviews (3)

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Reviews
02/15/2021

    High affinity binding.

    09/05/2020

      Stable in solution.

      02/20/2017

        Effective in hematopoiesis studies.

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