Species : |
Human |
Source : |
E.coli |
Tag : |
His&T7 |
Protein Length : |
Ile20~Ala155 |
Description : |
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. |
Form : |
Freeze-dried powder |
Molecular Mass : |
Predicted Molecular Mass: 19.4kDa |
Endotoxin : |
<1.0EU per 1µg (determined by the LAL method) |
Purity : |
> 95% |
Characteristic : |
The isoelectric point is 9. |
Applications : |
SDS-PAGE; WB; ELISA; IP |
Stability : |
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : |
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : |
Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl |
Reconstitution : |
Reconstitute in sterile PBS, pH7.2-pH7.4 |