Recombinant Human IL18 Protein, His-tagged
| Cat.No. : | IL18-2297H |
| Product Overview : | Recombinant Human IL18 Protein (Arg94-Asp193) with a N-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
| Description : | The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : | E. coli |
| Species : | Human |
| Tag : | N-His |
| Form : | Freeze-dried powder |
| Molecular Mass : | Predicted Molecular Mass: 15.3 kDa Accurate Molecular Mass: 15 kDa |
| Protein length : | Arg94-Asp193 |
| Endotoxin : | <1.0 EU per 1µg (determined by the LAL method). |
| Purity : | > 95% |
| Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
| Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
| Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
| Storage Buffer : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
| Reconstitution : | Reconstitute in PBS or others. |
| Gene Name : | IL18 interleukin 18 (interferon-gamma-inducing factor) [ Homo sapiens (human) ] |
| Official Symbol : | IL18 |
| Synonyms : | IL18; interleukin 18 (interferon-gamma-inducing factor); interleukin-18; IGIF; IL 1g; IL 18; IL1F4; IL-1 gamma; iboctadekin; interleukin-1 gamma; IFN-gamma-inducing factor; IL-18; IL-1g; MGC12320; |
| Gene ID : | 3606 |
| mRNA Refseq : | NM_001243211 |
| Protein Refseq : | NP_001230140 |
| MIM : | 600953 |
| UniProt ID : | Q14116 |
Products Types
| ◆ Lysates | ||
| IL18-344HCL | Recombinant Human IL18 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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